Anti-Influenza agent 4

• 常用名: Anti-Influenza agent 4
• 英文名: Anti-Influenza agent 4
• CAS号: 522625-85-0
• 分子量: 386.42
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₈N₂O₅S
• 熔点: N/A
• 闪点: N/A

Anti-Influenza agent 4用途

抗流感剂4是一种有效和选择性的流感病毒抑制剂,对a/Roma和a/Parma株的EC50分别为150 nM和62 nM[1]。

Anti-Influenza agent 4名称

• 英文名: Benzamide, N-[3-[[(2-furanylmethyl)amino]sulfonyl]phenyl]-4-methoxy

Anti-Influenza agent 4生物活性

• 描述: 抗流感剂4是一种有效和选择性的流感病毒抑制剂,对a/Roma和a/Parma株的EC50分别为150 nM和62 nM[1]。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 靶点实验:

  EC50: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma)[1]

• 体外研究: 抗流感剂4(化合物5)(0-500μM；24和48小时)在MDCK细胞中表现出低细胞毒性[1]。抗流感剂4显示出对流感毒株A/Roma和A/Parma的高度抗病毒活性,EC50分别为150±0.07 nM和62±0.02 nM[1]。在溶血抑制试验中,抗流感剂4对流感毒株A/Roma和A/Parma的IC50分别为244 nM和230.7 nM[1]。细胞毒性试验[1]细胞系：MDCK细胞浓度：0-500μM培养时间：24和48小时结果：显示出低细胞毒性,CC50值为450μM。

Anti-Influenza agent 4物理化学性质

• 分子式: C₁₉H₁₈N₂O₅S
• 分子量: 386.42
• InChIKey: HBZICUMXNDTDSI-UHFFFAOYSA-N
• SMILES: COc1ccc(C(=O)Nc2cccc(S(=O)(=O)NCc3ccco3)c2)cc1
• 储存条件: -20°C

Anti-Influenza agent 4靶点实验

查看更多实验

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