(R)-DPN
Modify Date: 2024-01-31 21:23:51
(R)-DPN structure
|
Common Name | (R)-DPN | ||
|---|---|---|---|---|
| CAS Number | 524047-78-7 | Molecular Weight | 239.269 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 449.4±35.0 °C at 760 mmHg | |
| Molecular Formula | C15H13NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 225.6±25.9 °C | |
Use of (R)-DPNR)-DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R)-DPN shows a very high affinity and potency preference for ERβ over ERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively[1]. |
| Name | (r)-dpn |
|---|---|
| Synonym | More Synonyms |
| Description | R)-DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R)-DPN shows a very high affinity and potency preference for ERβ over ERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
ERα:2.9 nM (EC50) ERβ:0.8 nM (EC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 449.4±35.0 °C at 760 mmHg |
| Molecular Formula | C15H13NO2 |
| Molecular Weight | 239.269 |
| Flash Point | 225.6±25.9 °C |
| Exact Mass | 239.094635 |
| PSA | 64.25000 |
| LogP | 2.06 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.640 |
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