2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl]

Modify Date: 2025-08-27 16:33:20

2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl] Structure
2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl] structure
Common Name 2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl]
CAS Number 526-02-3 Molecular Weight 275.30000
Density 1.232g/cm3 Boiling Point 498.7ºC at 760mmHg
Molecular Formula C15H17NO4 Melting Point N/A
MSDS N/A Flash Point 255.4ºC

 Names

Name 3-(2-Hydroxy-3,5-dimethylphenacyl)glutarimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.232g/cm3
Boiling Point 498.7ºC at 760mmHg
Molecular Formula C15H17NO4
Molecular Weight 275.30000
Flash Point 255.4ºC
Exact Mass 275.11600
PSA 83.47000
LogP 1.96340
InChIKey YTLMIHBTPWTPEV-UHFFFAOYSA-N
SMILES Cc1cc(C)c(O)c(C(=O)CC2CC(=O)NC(=O)C2)c1

 Safety Information

HS Code 2925190090

 Synthetic Route

~67%

2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl] Structure

2,6-Piperidined...

CAS#:526-02-3

Literature: Lakhvich, F. A.; Buravskaya, T. N.; Akhrem, A. A. Chemistry of Natural Compounds, 1993 , vol. 29, # 4 p. 526 - 529 Khimiya Prirodnykh Soedinenii, 1993 , # 4 p. 598 - 602

~53%

2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl] Structure

2,6-Piperidined...

CAS#:526-02-3

Literature: Ji, Xing-Yue; Zhong, Zhao-Jin; Xue, Si-Tu; Meng, Shuai; He, Wei-Ying; Gao, Rong-Mei; Li, Yu-Huan; Li, Zhuo-Rong Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 11 p. 1436 - 1441

~9%

2,6-Piperidinedione, 4-[2- (2-hydroxy-3,5-dimethylphenyl)-2-oxoethyl] Structure

2,6-Piperidined...

CAS#:526-02-3

Literature: Kiyota, Hiromasa; Shimizu, Yuko; Oritani, Takayuki Tetrahedron Letters, 2000 , vol. 41, # 31 p. 5887 - 5890

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Bioassay

View more

Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate ...
Source: Broad Institute
Target: N/A
External Id: 7056-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based biochemical high throughput primary assay to identify inhibitors o...
Source: The Scripps Research Institute Molecular Screening Center
Target: Phospholipase C, beta 3 (phosphatidylinositol-specific) [Homo sapiens]
External Id: PLCB3_INH_QFRET_1536_1X%INH PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: ADAM10 [Homo sapiens]
External Id: ADAM10_INH_QFRET_1536_1X%INH PRUN
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: abhydrolase domain-containing protein 4 isoform 1 [Mus musculus]
External Id: ABHD4_INH_FP_1536_1X%INH PRUN
Name: Counterscreen for antagonists of COUP-TFII (NR2F2): Luminescence-based cell-based hig...
Source: The Scripps Research Institute Molecular Screening Center
Target: transactivating tegument protein VP16 [Human herpesvirus 1]
External Id: VP16_INH_LUMI_1536_3X%INH CSRUN for COUP-TFII (NR2F2)
Name: Luminescence-based cell-based primary high throughput screening assay to identify inh...
Source: The Scripps Research Institute Molecular Screening Center
Target: COUP transcription factor 2 isoform a [Homo sapiens]
External Id: COUPTFII_INH_LUMI_1536_1X%INH PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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 Synonyms

4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione
Actiphenol
4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]-2,6-piperidinedione
Actinophenol
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