5-Acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile structure
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Common Name | 5-Acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile | ||
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CAS Number | 52600-53-0 | Molecular Weight | 176.17200 | |
Density | 1.25g/cm3 | Boiling Point | 359.4ºC at 760mmHg | |
Molecular Formula | C9H8N2O2 | Melting Point | 233-235ºC | |
MSDS | N/A | Flash Point | N/A |
Name | 5-acetyl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile |
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Synonym | More Synonyms |
Density | 1.25g/cm3 |
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Boiling Point | 359.4ºC at 760mmHg |
Melting Point | 233-235ºC |
Molecular Formula | C9H8N2O2 |
Molecular Weight | 176.17200 |
Exact Mass | 176.05900 |
PSA | 73.98000 |
LogP | 1.16988 |
Index of Refraction | 1.546 |
Synonym:5-Acetyl-3-cyano-6-methyl-2-pyridon Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 52600-53-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: tan Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 226 - 228 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H8N2O2 Molecular Weight: 176 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Bases, oxidizing agents. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 52600-53-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 5-Acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.* Hazard Class: 6.1 UN Number: 3276 Packing Group: III IMO Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing Group: III RID/ADR Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. WGK (Water Danger/Protection) CAS# 52600-53-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 52600-53-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 52600-53-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
~45% 5-Acetyl-6-meth... CAS#:52600-53-0 |
Literature: Abu-Shanab; Redhouse; Thompson; Wakefield Synthesis, 1995 , # 5 p. 557 - 560 |
~43% 5-Acetyl-6-meth... CAS#:52600-53-0 |
Literature: Merrell Dow Pharmaceuticals Inc. Patent: US4568751 A1, 1986 ; |
~92% 5-Acetyl-6-meth... CAS#:52600-53-0 |
Literature: Mosti, Luisa; Schenone, Pietro; Menozzi, Giulia Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1503 - 1509 |
~86% 5-Acetyl-6-meth... CAS#:52600-53-0 |
Literature: Mosti, Luisa; Schenone, Pietro; Menozzi, Giulia Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1503 - 1509 |
~% 5-Acetyl-6-meth... CAS#:52600-53-0 |
Literature: Jones Jr.; Schnettler; Huber Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 511 - 518 |
~% 5-Acetyl-6-meth... CAS#:52600-53-0
Detail
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Literature: Sterling Drug Inc. Patent: US4469699 A1, 1984 ; |
~%
Detail
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Literature: Sterling Drug Inc. Patent: US4469699 A1, 1984 ; |
~% 5-Acetyl-6-meth... CAS#:52600-53-0 |
Literature: Jones Jr.; Schnettler; Huber Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 511 - 518 |
Precursor 6 | |
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DownStream 10 | |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
5-acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile |
5-acetyl-6-methyl-1,2-dihydro-2-oxo-3-pyridinecarbonitrile |
5-Acetyl-2-hydroxy-6-methylnicotinonitrile |
5-acetyl-2-hydroxy-6-methylpyridine-3-carbonitrile |
5-acetyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile |
3-cyano-5-acetyl-6-methylpyridin-2(1H)-one |
5-acetyl-1,2-dihydro-6-methyl-2-oxonicotinonitrile |