isoxanthopterin

Modify Date: 2026-07-17 14:15:16

isoxanthopterin Structure
isoxanthopterin structure
Common Name isoxanthopterin
CAS Number 529-69-1 Molecular Weight 179.13600
Density 2.17g/cm3 Boiling Point 686.5ºC at 760mmHg
Molecular Formula C6H5N5O2 Melting Point N/A
MSDS Chinese USA Flash Point 369ºC

 Use of isoxanthopterin


Isoxanthopterin is a natural intermediate in the pteridine pathway, which has roles in pigmentation and cell division.

 Names

Name 2-aminopteridine-4,7-diol
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.17g/cm3
Boiling Point 686.5ºC at 760mmHg
Molecular Formula C6H5N5O2
Molecular Weight 179.13600
Flash Point 369ºC
Exact Mass 179.04400
PSA 117.52000
Appearance of Characters powder | off-white
Index of Refraction 1.991
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO3425000
CHEMICAL NAME :
4,7(3H,8H)-Pteridinedione, 2-amino-
CAS REGISTRY NUMBER :
529-69-1
LAST UPDATED :
199409
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H5-N5-O2
MOLECULAR WEIGHT :
179.16
WISWESSER LINE NOTATION :
T66 BMV EN GVM JNJ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Fish - salmon Sperm
DOSE/DURATION :
28 umol/L/4D (Continuous)
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 58,1541,1967

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 22-24/25-36-26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UO3425000
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles30

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The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Normalization of urinary pteridines by urine specific gravity for early cancer detection.

Clin. Chim. Acta 435 , 42-7, (2014)

Urinary biomarkers, such as pteridines, require normalization with respect to an individual's hydration status and time since last urination. Conventional creatinine-based corrections are affected by ...

Direct radical scavenging activity of benzbromarone provides beneficial antioxidant properties for hyperuricemia treatment.

Biol. Pharm. Bull. 38(3) , 487-92, (2015)

Uric acid exerts an important antioxidant effect against external oxidative stress under physiological conditions. However, uric acid itself can increase oxidative stress via reduced nicotinamide aden...

 isoxanthopterinBioassay

View more

Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2
Source: NCGC
Target: eyes absent homolog 2 isoform a [Homo sapiens]
External Id: EYA2477
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2...
Source: NCGC
Target: ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens]
External Id: UBCH001
Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
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 Synonyms

MFCD00006696
2-Aminopteridine-4,7-diol
2-amino-3H,8H-pteridine-4,7-dione
2-Amino-3H,8H-pteridin-4,7-dion
2-Amino-4,7-pteridinediol
2-Amino-4,7(3H,8H)pteridindion
2-Amino-4,7-dihydroxypteridine
2-amino-1,8-dihydropteridine-4,7-dione
EINECS 208-469-5
4,7(3H,8H)-Pteridinedione,2-amino
Isoxanthopterin
Ranachrome 4
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