XIB-4035

Modify Date: 2024-01-02 15:48:57

XIB-4035 Structure
XIB-4035 structure
Common Name XIB-4035
CAS Number 529507-84-4 Molecular Weight 456.450
Density 1.2±0.1 g/cm3 Boiling Point 597.1±50.0 °C at 760 mmHg
Molecular Formula C26H31Cl2N3 Melting Point N/A
MSDS USA Flash Point 314.9±30.1 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of XIB-4035


A nonpeptidyl small molecule agonist of GDNF family receptor α1 (GFRα-1); concentration-dependently inhibits [(125)I]GDNF binding in Neuro-2A cells with IC50 of 10.4 uM; induces autophosphorylation of Ret protein, promotes neurite outgrowth in Neuro-2A cells, and induces Ret autophosphorylation in the Neuro-2A cells.

 Names

Name aminoquinol
Synonym More Synonyms

 XIB-4035 Biological Activity

Description A nonpeptidyl small molecule agonist of GDNF family receptor α1 (GFRα-1); concentration-dependently inhibits [(125)I]GDNF binding in Neuro-2A cells with IC50 of 10.4 uM; induces autophosphorylation of Ret protein, promotes neurite outgrowth in Neuro-2A cells, and induces Ret autophosphorylation in the Neuro-2A cells.
References References 1. Hedstrom KL, et al. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2325-30. 2. Tokugawa K, et al. Neurochem Int. 2003 Jan;42(1):81-6. 3. Höke A. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2060-1. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 597.1±50.0 °C at 760 mmHg
Molecular Formula C26H31Cl2N3
Molecular Weight 456.450
Flash Point 314.9±30.1 °C
Exact Mass 455.189514
LogP 7.69
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.650

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H413
Precautionary Statements P301 + P310 + P330
RIDADR UN 2811 6.1 / PGIII

 Synonyms

AMINOQUINOL, (R)-
AMINOQUINOL, (S)-
N4-{7-Chloro-2-[(E)-2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediamine
N4-[7-Chloro-2-[(1E)-2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-1,4-pentanediamine
aminoquinol
MFCD00601670
UNII:CH1Y88E2AY
1,4-Pentanediamine, N4-[7-chloro-2-[(E)-2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-
CH1Y88E2AY
N4-{7-Chloro-2-[(E)-2-(2-chlorophenyl)vinyl]quinolin-4-yl}-N1,N1-diethylpentane-1,4-diamine
N-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N-[4-(diethylamino)-1-methylbutyl]amine
N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quin olin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine
XIB4035
Top Suppliers:I want be here



Get all suppliers and price by the below link:

XIB-4035 suppliers

XIB-4035 price