Fluprednisolone

Modify Date: 2026-08-15 10:40:05

Fluprednisolone structure	Common Name	Fluprednisolone
	CAS Number	53-34-9	Molecular Weight	378.43400
	Density	1.35 g/cm3	Boiling Point	572.3ºC at 760 mmHg
	Molecular Formula	C₂₁H₂₇FO₅	Melting Point	208 - 213ºC
	MSDS	N/A	Flash Point	299.9ºC

Use of Fluprednisolone

6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97. [2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82. [3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97.

[2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82.

[3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.35 g/cm3
Boiling Point	572.3ºC at 760 mmHg
Melting Point	208 - 213ºC
Molecular Formula	C₂₁H₂₇FO₅
Molecular Weight	378.43400
Flash Point	299.9ºC
Exact Mass	378.18400
PSA	94.83000
LogP	1.50560
Index of Refraction	1.597
InChIKey	MYYIMZRZXIQBGI-HVIRSNARSA-N
SMILES	CC12C=CC(=O)C=C1C(F)CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Fluprednisolone MSDS(Chinese)

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

Pregn-4-ene-3,2...

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Literature: Chemistry and Industry (London, United Kingdom), , p. 1002 US2838537 , ;

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Fluprednisolone

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Literature: Chemistry and Industry (London, United Kingdom), , p. 1002

21-acetoxy-6β-f...

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This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 1
CAS#:1058-55-5 Pregn-4-ene-3,2...
DownStream 0

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

Total 263, Current Page 1 of 27

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

F. I. 6150

fluprednisolone

EINECS 200-170-8

MFCD00200355

Isopredon

Prednisolone,6alpha-fluoro

6alpha-Fluoroprednisolone

Etadrol

Vladicort

Alphadrol

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular formula of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Molecular formula of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is C21H27FO5.

Q: What are the uses of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Main uses of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one: 6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].

Q: What is the InChIKey of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: InChIKey of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is MYYIMZRZXIQBGI-HVIRSNARSA-N.

Q: What is the boiling point of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Boiling point of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is 572.3ºC at 760 mmHg.

Q: What English synonyms does (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one have?

A: English synonyms of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one: F. I. 6150, fluprednisolone, EINECS 200-170-8, MFCD00200355, Isopredon, Prednisolone,6alpha-fluoro, 6alpha-Fluoroprednisolone, Etadrol, Vladicort, Alphadrol.

Q: What is the molecular weight of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Molecular weight of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is 378.43400.

Q: What is the CAS number of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: CAS number of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is 53-34-9.

Q: What is the polar surface area (PSA) of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Polar surface area (PSA) of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is 94.83000.

Q: What is the melting point of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Melting point of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one is 208 - 213ºC.

Q: What are the upstream materials of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one?

A: Related upstream materials(CAS) of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one: 1058-55-5.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Fluprednisolone
Price: Check
Purity: 98.44%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fluprednisolone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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