DiSC3(5)

Modify Date: 2024-01-04 10:06:34

DiSC3(5) Structure
DiSC3(5) structure
Common Name DiSC3(5)
CAS Number 53213-94-8 Molecular Weight 546.53000
Density N/A Boiling Point N/A
Molecular Formula C25H27IN2S2 Melting Point 245ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of DiSC3(5)


DiSC3(5) is a fluorescent probe often used as a tracer dye to assess the mitochondrial membrane potential[1].

 Names

Name 3,3'-Dipropylthiadicarbocyanine Iodide
Synonym More Synonyms

 DiSC3(5) Biological Activity

Description DiSC3(5) is a fluorescent probe often used as a tracer dye to assess the mitochondrial membrane potential[1].
Related Catalog
References

[1]. Yamamoto T, et al. Multiple effects of DiS-C3(5) on mitochondrial structure and function. Eur J Biochem. 2004;271(17):3573-3579.

 Chemical & Physical Properties

Melting Point 245ºC (dec.)(lit.)
Molecular Formula C25H27IN2S2
Molecular Weight 546.53000
Exact Mass 546.06600
PSA 65.29000
LogP 3.36020

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Articles14

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A short-chain alkyl derivative of Rhodamine 19 acts as a mild uncoupler of mitochondria and a neuroprotector.

Biochim. Biophys. Acta 1837(10) , 1739-47, (2014)

Limited uncoupling of oxidative phosphorylation is known to be beneficial in various laboratory models of diseases. The search for cationic uncouplers is promising as their protonophorous effect is se...

Myricetin inhibits the release of glutamate in rat cerebrocortical nerve terminals.

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The excessive release of glutamate is a critical element in the neuropathology of acute and chronic brain disorders. The purpose of the present study was to investigate the effect and possible mechani...

 Synonyms

MFCD00075033
3-Propyl-2-[5-[3-propyl-2(3H)-benzothiazolylidene]-1,3-pentadienyl]benzothiazolium Iodide
3,3'-Dipropylthiadicarbocyanine iodide
3,3'-Dipropylthiadicarbocyanine iodide,DiSC3(5)
5-(3-Propylbenzothiazol-2-ylidene)-1-(3-propylbenzothiazolium-2-yl)-1,3-pentadiene Iodide