PP3
PP3 structure
|
Common Name | PP3 | ||
|---|---|---|---|---|
| CAS Number | 5334-30-5 | Molecular Weight | 211.223 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 364.0±35.0 °C at 760 mmHg | |
| Molecular Formula | C11H9N5 | Melting Point | 214-217 °C | |
| MSDS | N/A | Flash Point | 173.9±25.9 °C | |
Use of PP3PP 3 (Compound 3) is an EGFR tyrosine kinase inhibitor with an IC50 of 2.7 μM[1]. |
| Name | 4-amino-1-phenylpyrazolo[3,4-d]pyrimidine |
|---|---|
| Synonym | More Synonyms |
| Description | PP 3 (Compound 3) is an EGFR tyrosine kinase inhibitor with an IC50 of 2.7 μM[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 364.0±35.0 °C at 760 mmHg |
| Melting Point | 214-217 °C |
| Molecular Formula | C11H9N5 |
| Molecular Weight | 211.223 |
| Flash Point | 173.9±25.9 °C |
| Exact Mass | 211.085800 |
| PSA | 69.62000 |
| LogP | 1.59 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.770 |
| Storage condition | -20°C |
| Hazard Codes | Xn,Xi |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | S36/37/39-S26 |
| HS Code | 2933990090 |
|
~80%
PP3 CAS#:5334-30-5 |
| Literature: Rahmouni, Ameur; Romdhane, Anis; Ben Said, Abderrahim; Majouli, Kaouther; Ben Jannet, Hichem Turkish Journal of Chemistry, 2014 , vol. 38, # 2 p. 210 - 221 |
|
~67%
PP3 CAS#:5334-30-5 |
| Literature: Karoui, Amine; Allouche, Fatma; Deghrigue, Monia; Agrebi, Asma; Bouraoui, Abderrahman; Chabchoub, Fakher Medicinal Chemistry Research, 2014 , vol. 23, # 3 p. 1591 - 1598 |
|
~%
PP3 CAS#:5334-30-5 |
| Literature: Journal of Organic Chemistry, , vol. 21, p. 1240,1242 |
|
~%
PP3 CAS#:5334-30-5 |
| Literature: Journal of Organic Chemistry, , vol. 21, p. 1240,1242 |
|
~%
PP3 CAS#:5334-30-5 |
| Literature: Medicinal Chemistry Research, , vol. 23, # 3 p. 1591 - 1598 |
![4-Chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/306/5334-48-5.png)
| Precursor 5 | |
|---|---|
| DownStream 10 | |
![4H-Pyrazolo[3,4-d]pyrimidin-4-one,1,5-dihydro-1-phenyl- structure](https://image.chemsrc.com/caspic/003/21314-17-0.png)
CAS#:21314-17-0![4-(4-chlorophenyl)-1-phenylpyrazolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/489/87412-79-1.png)
CAS#:87412-79-1![4-(2-chlorophenyl)-1-phenylpyrazolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/027/87412-78-0.png)
CAS#:87412-78-0
CAS#:87412-77-9![1,4-diphenylpyrazolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/178/53645-78-6.png)
CAS#:53645-78-6![4-(4-methoxyphenyl)-1-phenylpyrazolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/113/87412-76-8.png)
CAS#:87412-76-8
CAS#:87412-74-6![4-(2-methoxyphenyl)-1-phenylpyrazolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/151/87412-75-7.png)
CAS#:87412-75-7
CAS#:87412-72-4
CAS#:87412-73-5| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-phenyl- |
| 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine |
| MFCD00022901 |
| 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| 1-phenylpyrazolo[3,4-d]pyrimidin-4-amine |
| 4-Amino-1-phenylpyrazole[3,4-d]pyrimidine |
| PP3 |