rac 4-Hydroxy-3-methoxyphenylethylene Glycol

Modify Date: 2024-01-09 09:59:05

rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure
rac 4-Hydroxy-3-methoxyphenylethylene Glycol structure
Common Name rac 4-Hydroxy-3-methoxyphenylethylene Glycol
CAS Number 534-82-7 Molecular Weight 184.19
Density N/A Boiling Point N/A
Molecular Formula C9H12O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of rac 4-Hydroxy-3-methoxyphenylethylene Glycol


3-Methoxy-4-hydroxyphenylglycol (HMPG) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol can be used for research of depression, chronic schizophrenia, etc[1].

 Names

Name rac 4-Hydroxy-3-methoxyphenylethylene Glycol
Synonym More Synonyms

  Biological Activity

Description 3-Methoxy-4-hydroxyphenylglycol (HMPG) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol can be used for research of depression, chronic schizophrenia, etc[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Lambert GW, et al. Regional origins of 3-methoxy-4-hydroxyphenylglycol in plasma: effects of chronic sympathetic nervous activation and denervation, and acute reflex sympathetic stimulation. J Auton Nerv Syst. 1995 Nov 6;55(3):169-78.  

 Chemical & Physical Properties

Molecular Formula C9H12O4
Molecular Weight 184.19
Exact Mass 187.09200
PSA 69.92000
LogP 0.42650

 Safety Information

HS Code 2909499000

 Synthetic Route

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rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Benigni,J.D.; Verbiscar,A.J. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608

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rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Benigni,J.D.; Verbiscar,A.J. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608

~%

rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Benigni,J.D.; Verbiscar,A.J. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608

~%

rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Benigni,J.D.; Verbiscar,A.J. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608

~46%

rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Holshouser; Kolb Journal of Pharmaceutical Sciences, 1986 , vol. 75, # 6 p. 619 - 621

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rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Jerkeman,P.; Lindberg,B. Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1477 - 1482

~%

rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Jerkeman,P.; Lindberg,B. Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1477 - 1482

~%

rac 4-Hydroxy-3-methoxyphenylethylene Glycol Structure

rac 4-Hydroxy-3...

CAS#:534-82-7

Literature: Jerkeman,P.; Lindberg,B. Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1477 - 1482

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

4-hydroxy-3-methoxy-d3-phenylethylene glycol
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