5-Chloro-2-thiophenesulfonamide

Modify Date: 2024-01-05 09:18:00

5-Chloro-2-thiophenesulfonamide structure	Common Name	5-Chloro-2-thiophenesulfonamide
	CAS Number	53595-66-7	Molecular Weight	197.663
	Density	1.6±0.1 g/cm3	Boiling Point	366.3±52.0 °C at 760 mmHg
	Molecular Formula	C₄H₄ClNO₂S₂	Melting Point	113-117 °C(lit.)
	MSDS	Chinese USA	Flash Point	175.3±30.7 °C
	Symbol	GHS07	Signal Word	Warning

Name	5-Chlorothiophene-2-sulfonamide
Synonym	More Synonyms

Density	1.6±0.1 g/cm3
Boiling Point	366.3±52.0 °C at 760 mmHg
Melting Point	113-117 °C(lit.)
Molecular Formula	C₄H₄ClNO₂S₂
Molecular Weight	197.663
Flash Point	175.3±30.7 °C
Exact Mass	196.937195
PSA	96.78000
LogP	0.94
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.621

5-Chloro-2-thiophenesulfonamide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XN0296000

CHEMICAL NAME :: 2-Thiophenesulfonamide, 5-chloro-

CAS REGISTRY NUMBER :: 53595-66-7

BEILSTEIN REFERENCE NO. :: 0130728

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C4-H4-Cl-N-O2-S2

MOLECULAR WEIGHT :: 197.66

WISWESSER LINE NOTATION :: T5SJ BG ESWZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 19,449,1961

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S45-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2935009090

5-Chlorothiophe...

CAS#:2766-74-7

~92%

5-Chloro-2-thio...

CAS#:53595-66-7

Literature: WO2011/92226 A1, ; Page/Page column 33 ; WO 2011/092226 A1

2-thienylsulfon...

CAS#:16629-19-9

5-Chloro-2-thio...

CAS#:53595-66-7

Literature: WO2003/99316 A1, ; Page 61 ; WO 03/099316 A1

Precursor 2
CAS#:2766-74-7 5-Chlorothiophe... CAS#:16629-19-9 2-thienylsulfon...
DownStream 1
CAS#:849793-87-9 Ethyl5-chloroth...

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Sulfonamide derivatives of bridgehead substituted bicyclo[4.2.1]nonanes as gamma-secretase inhibitors.

Bioorg. Med. Chem. Lett. 18(1) , 375-9, (2008)

Bridgehead substituted derivatives of bicyclo[4.2.1]nonanes were synthesized and shown to be potent inhibitors of gamma-secretase. Two related series were synthesized to explore the SARs. More potent ...

Rhodium-catalyzed aerobic N-alkylation of sulfonamides with alcohols. Feng SL, et al.

Chin. Chem. Lett. 22(9) , 1021-1024., (2011)

MFCD00052584

2-Thiophenesulfonamide, 5-chloro-

2-Chloro-5-sulfamoylthiophene

T5SJ BSZW EG

5-Chloro-2-thiophenesulfonamide

5-chlorothiophene-2-sulfonamide

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-Chloro-2-thiophenesulfonamide
Price: ￥278.0/5g ￥88.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Chlorothiophene-2-sulfonamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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5-Chloro-2-thiophenesulfonamide

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

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