vindesine
Modify Date: 2026-06-30 23:56:52
vindesine structure
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Common Name | vindesine | ||
|---|---|---|---|---|
| CAS Number | 53643-48-4 | Molecular Weight | 753.926 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C43H55N5O7 | Melting Point | 230-232ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of vindesineVindesine is a semisynthetic derivative of vinblastine. Vindesine is a potent anticancer agent. Vindesine can be used for the research of melanoma and lung cancers[1]. |
| Name | vindesine |
|---|---|
| Synonym | More Synonyms |
| Description | Vindesine is a semisynthetic derivative of vinblastine. Vindesine is a potent anticancer agent. Vindesine can be used for the research of melanoma and lung cancers[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Chabner BA, et al. Vinca alkaloids. Cancer Chemother Biol Response Modif. 1991;12:67-73. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Melting Point | 230-232ºC |
| Molecular Formula | C43H55N5O7 |
| Molecular Weight | 753.926 |
| Exact Mass | 753.410156 |
| PSA | 164.82000 |
| LogP | 2.94 |
| Index of Refraction | 1.708 |
| InChIKey | HHJUWIANJFBDHT-KOTLKJBCSA-N |
| SMILES | CCC1(O)CC2CN(CCc3c([nH]c4ccccc34)C(C(=O)OC)(c3cc4c(cc3OC)N(C)C3C(O)(C(N)=O)C(O)C5(CC)C=CCN6CCC43C65)C2)C1 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| RIDADR | UN 1544 |
|---|---|
| Packaging Group | II |
| Hazard Class | 6.1(a) |
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Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
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|
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
|
|
Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
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|
Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
|
|
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
|
|
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
|
|
Name: Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H...
Source: Southern Research Institute
Target: CFTR
External Id: CF Folding
|
|
Name: MELAS cybrid survival enhancement under low glucose conditions
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1419
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|
Name: Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu...
Source: 15621
Target: G protein-activated inward rectifier potassium channel 2
External Id: VANDERBILT_HTS_GIRK2_MPD
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| Vindesin |
| EINECS 258-682-2 |
| methyl (5S,7S,9S)-9-[(2β,3β,4β,5α,12β,19α)-3-(aminocarbonyl)-3,4-dihydroxy-1-methyl-16-(methyloxy)-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,14b-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate |
| Vindesinum |
| 4-Desacetylleurosidin-C-3-carboxamid |
| Vindesina |
| Methyl (13S,15S,17S)-13-[(2β,3β,4β,5α,12β,19α)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0.0]nonadeca-5,7,9,11-tetraene-13-carboxylate |
| Desacetylvinblastine amide |
| Eldesine |