vindesine

Modify Date: 2025-08-21 17:36:39

vindesine structure	Common Name	vindesine
	CAS Number	53643-48-4	Molecular Weight	753.926
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₃H₅₅N₅O₇	Melting Point	230-232ºC
	MSDS	N/A	Flash Point	N/A

Use of vindesine

Vindesine is a semisynthetic derivative of vinblastine. Vindesine is a potent anticancer agent. Vindesine can be used for the research of melanoma and lung cancers[1].

Name	vindesine
Synonym	More Synonyms

Description	Vindesine is a semisynthetic derivative of vinblastine. Vindesine is a potent anticancer agent. Vindesine can be used for the research of melanoma and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Chabner BA, et al. Vinca alkaloids. Cancer Chemother Biol Response Modif. 1991;12:67-73.

Density	1.4±0.1 g/cm3
Melting Point	230-232ºC
Molecular Formula	C₄₃H₅₅N₅O₇
Molecular Weight	753.926
Exact Mass	753.410156
PSA	164.82000
LogP	2.94
Index of Refraction	1.708

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YY8080000

CHEMICAL NAME :: Vincaleukoblastine, 3-(aminocarbonyl)-O(sup 4)-deacetyl-3-de(methoxycarbonyl)-

CAS REGISTRY NUMBER :: 53643-48-4

LAST UPDATED :: 199504

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C43-H55-N5-O7

MOLECULAR WEIGHT :: 754.03

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13800 ug/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TEST SYSTEM :: Rodent - hamster

DOSE/DURATION :: 1100 ug/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 174,11,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7287 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14 (estimated) No. of Female Employees: 14 (estimated)

RIDADR	UN 1544
Packaging Group	II
Hazard Class	6.1(a)

2H-3,7-Methanoazacycloundecino[5,4-b]indole-9-carboxylic acid, 9-[(2β,3β,4β,5α,12β,19α)-3-(aminocarbonyl)-6,7-didehydro-3,4-dihydroxy-16-methoxy-1-methylaspidospermidin-15-yl]-5-et hyl-1,4,5,6,7,8,9,14b-octahydro-5-hydroxy-, methyl ester, (5S,7S,9S)-

Vindesin

EINECS 258-682-2

methyl (5S,7S,9S)-9-[(2β,3β,4β,5α,12β,19α)-3-(aminocarbonyl)-3,4-dihydroxy-1-methyl-16-(methyloxy)-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,14b-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate

Vindesinum

4-Desacetylleurosidin-C-3-carboxamid

Vindesina

Methyl (13S,15S,17S)-13-[(2β,3β,4β,5α,12β,19α)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0.0]nonadeca-5,7,9,11-tetraene-13-carboxylate

Desacetylvinblastine amide

Eldesine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: vindesine
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
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vindesine

Use of vindesine

Names

vindesine Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.