vindesine

Modify Date: 2024-01-05 07:06:41

vindesine structure	Common Name	vindesine
	CAS Number	53643-48-4	Molecular Weight	753.926
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₃H₅₅N₅O₇	Melting Point	230-232ºC
	MSDS	N/A	Flash Point	N/A

Use of vindesine

Vindesine is a semisynthetic derivative of vinblastine. Vindesine is a potent anticancer agent. Vindesine can be used for the research of melanoma and lung cancers[1].

Name	vindesine
Synonym	More Synonyms

Description	Vindesine is a semisynthetic derivative of vinblastine. Vindesine is a potent anticancer agent. Vindesine can be used for the research of melanoma and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Chabner BA, et al. Vinca alkaloids. Cancer Chemother Biol Response Modif. 1991;12:67-73.

Density	1.4±0.1 g/cm3
Melting Point	230-232ºC
Molecular Formula	C₄₃H₅₅N₅O₇
Molecular Weight	753.926
Exact Mass	753.410156
PSA	164.82000
LogP	2.94
Index of Refraction	1.708

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YY8080000

CHEMICAL NAME :: Vincaleukoblastine, 3-(aminocarbonyl)-O(sup 4)-deacetyl-3-de(methoxycarbonyl)-

CAS REGISTRY NUMBER :: 53643-48-4

LAST UPDATED :: 199504

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C43-H55-N5-O7

MOLECULAR WEIGHT :: 754.03

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13800 ug/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TEST SYSTEM :: Rodent - hamster

DOSE/DURATION :: 1100 ug/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 174,11,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7287 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14 (estimated) No. of Female Employees: 14 (estimated)

RIDADR	UN 1544
Packaging Group	II
Hazard Class	6.1(a)

2H-3,7-Methanoazacycloundecino[5,4-b]indole-9-carboxylic acid, 9-[(2β,3β,4β,5α,12β,19α)-3-(aminocarbonyl)-6,7-didehydro-3,4-dihydroxy-16-methoxy-1-methylaspidospermidin-15-yl]-5-et hyl-1,4,5,6,7,8,9,14b-octahydro-5-hydroxy-, methyl ester, (5S,7S,9S)-

Vindesin

EINECS 258-682-2

methyl (5S,7S,9S)-9-[(2β,3β,4β,5α,12β,19α)-3-(aminocarbonyl)-3,4-dihydroxy-1-methyl-16-(methyloxy)-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,14b-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate

Vindesinum

4-Desacetylleurosidin-C-3-carboxamid

Vindesina

Methyl (13S,15S,17S)-13-[(2β,3β,4β,5α,12β,19α)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0.0]nonadeca-5,7,9,11-tetraene-13-carboxylate

Desacetylvinblastine amide

Eldesine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: vindesine
Price: Click To Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

vindesine suppliers

vindesine price

vindesine

Use of vindesine

Names

vindesine Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synonyms