Etonogestrel

Modify Date: 2025-08-23 23:33:30

Etonogestrel Structure
Etonogestrel structure
 Common Name Etonogestrel
CAS Number 54048-10-1 Molecular Weight 324.457
Density 1.1±0.1 g/cm3 Boiling Point 473.1±45.0 °C at 760 mmHg
Molecular Formula C22H28O2 Melting Point 182-184ºC
MSDS Chinese USA Flash Point 201.1±21.3 °C
Symbol GHS08
GHS08		 Signal Word Danger

 Names

Name etonogestrel
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 473.1±45.0 °C at 760 mmHg
Melting Point 182-184ºC
Molecular Formula C22H28O2
Molecular Weight 324.457
Flash Point 201.1±21.3 °C
Exact Mass 324.208923
PSA 37.30000
LogP 4.22
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.575
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JF8290000
CHEMICAL NAME :
18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)-
CAS REGISTRY NUMBER :
54048-10-1
LAST UPDATED :
198910
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H28-O2
MOLECULAR WEIGHT :
324.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
10500 ng/kg
SEX/DURATION :
female 21 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 17,19,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
50 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 35,459,1985

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H351-H360
Precautionary Statements P201-P280-P308 + P313
Hazard Codes Xn
Risk Phrases 60-40
RIDADR NONH for all modes of transport
RTECS JF8290000

 Synthetic Route

 Articles38

More Articles
Effect of progestins on immunity: medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCs.

Contraception 90(2) , 123-9, (2014)

The potential effect of hormonal contraception on HIV-1 acquisition and transmission represents an important public health issue. Several observational studies have suggested an association between th...

Newer non-oral hormonal contraception.

BMJ 346 , f341, (2013)

The combined etonogestrel/ethinyl estradiol contraceptive vaginal ring.

Expert Opin. Pharmacother. 8(11) , 1769-77, (2007)

Many factors influence the effectiveness of contraceptive methods. Oral contraceptives are the second most popular contraceptive method after female sterilization in the US. A total of 25% of women do...

 Synonyms

EINECS 258-936-2
3-Ketodesogestrel,3-Oxodesogestrel,Org-3236,Implanon
Etonoestrel
3-Keto-desogestrel 3-Oxo-desogestrel
(17a)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one
3-Oxodesogestrel
3-Keto-Org 2969
18,19-Dinor-17α-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-
3-keto-desogestrel
(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
13-Ethyl-17-hydroxy-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-3-one
3-Ketodesogestrel
Etonogestrel
Nexplanon
Desogestrel Related Compound C (25 mg) (3-Keto-desogestrel)
(8S,9S,10R,13S,14S,17R)-17-Ethinyl-13-ethyl-17-hydroxy-11-methyliden-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-on
UNII-304GTH6RNH
MFCD00867863
Implanon
[3H]-3-keto-Desogestrel
org3236
(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
17-Ethinyl-17b-hydroxy-18-methyl-11-methylene-4-estren-3-one
(8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-11-methylene-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
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Chemsrc provides Etonogestrel(CAS#:54048-10-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Etonogestrel are included as well.>> amp version: Etonogestrel

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