9H-Purine,6-(ethylthio)-

Modify Date: 2025-08-25 09:11:00

9H-Purine,6-(ethylthio)- Structure
9H-Purine,6-(ethylthio)- structure
Common Name 9H-Purine,6-(ethylthio)-
CAS Number 5417-84-5 Molecular Weight 180.23000
Density 1.39g/cm3 Boiling Point 460.2ºC at 760mmHg
Molecular Formula C7H8N4S Melting Point N/A
MSDS Chinese USA Flash Point 232.1ºC
Symbol GHS08
GHS08
Signal Word Warning

 Names

Name 6-ethylsulfanyl-7H-purine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.39g/cm3
Boiling Point 460.2ºC at 760mmHg
Molecular Formula C7H8N4S
Molecular Weight 180.23000
Flash Point 232.1ºC
Exact Mass 180.04700
PSA 79.76000
LogP 1.46490
Index of Refraction 1.758
InChIKey XTJLAIOQORFEOI-UHFFFAOYSA-N
SMILES CCSc1ncnc2nc[nH]c12

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO8535000
CHEMICAL NAME :
Purine, 6-(ethylthio)-
CAS REGISTRY NUMBER :
5417-84-5
LAST UPDATED :
198502
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H8-N4-S
MOLECULAR WEIGHT :
180.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
164 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,618,1982

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H351
Precautionary Statements P281
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn
Risk Phrases 40
Safety Phrases 22-36
RIDADR UN 2811 6.1/PG 3
RTECS UO8535000
HS Code 2933990090

 Synthetic Route

~%

9H-Purine,6-(ethylthio)- Structure

9H-Purine,6-(et...

CAS#:5417-84-5

Literature: Journal of the American Chemical Society, , vol. 81, p. 1898,1901 Journal of the American Chemical Society, , vol. 78, p. 5097,5098 Journal of the American Chemical Society, , vol. 80, p. 6697

~%

9H-Purine,6-(ethylthio)- Structure

9H-Purine,6-(et...

CAS#:5417-84-5

Literature: Journal of the American Chemical Society, , vol. 80, p. 6265,6266,6268,6269,6270

~%

9H-Purine,6-(ethylthio)- Structure

9H-Purine,6-(et...

CAS#:5417-84-5

Literature: Journal of Organic Chemistry, , vol. 24, p. 259,260

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
Induction of the c-ski proto-oncogene by phorbol ester correlates with induction of megakaryocyte differentiation.

Oncogene 9(5) , 1407-16, (1994)

Overexpression of v-ski blocks the terminal differentiation of chicken erythroblasts, and in cooperation with v-sea causes transformation of these cells, indicating that c-ski may play a role in regul...

6-ethylmercaptopurine-mediated growth inhibition of HL-60 cells in vitro irrespective of purine salvage.

Cancer Chemother. Pharmacol. 25(3) , 189-94, (1989)

A variety of purine analogs inhibit the growth and induce the differentiation of human promyelocytic leukemia (HL-60) cells that lack the purine salvage enzyme hypoxanthine-guanine phosphoribosyltrans...

Differential effect of 6-ethylmercaptopurine on c-myc expression in wild-type and HGPRT-deficient HL-60 cells.

Cancer Chemother. Pharmacol. 27(3) , 171-7, (1990)

A variety of compounds inhibit the growth and induce differentiation of human promyelocytic leukemia (HL-60) cells. HL-60 subclones that lack the purine salvage enzyme hypoxanthine-guanine phosphoribo...

 Synonyms

6-Ethylmercaptopurine
QA 69
6-ETHYLTHIOPURINE
6-Ethyl MP
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