Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-

Modify Date: 2022-04-08 09:51:08

Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)- structure	Common Name	Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-
	CAS Number	545-84-6	Molecular Weight	384.46900
	Density	1.32g/cm3	Boiling Point	542.9ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₈N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	282.1ºC

Use of Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-

(–)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 g/ml).

Name	voacangarine
Synonym	More Synonyms

Density	1.32g/cm3
Boiling Point	542.9ºC at 760 mmHg
Molecular Formula	C₂₂H₂₈N₂O₄
Molecular Weight	384.46900
Flash Point	282.1ºC
Exact Mass	384.20500
PSA	74.79000
LogP	2.17250
Index of Refraction	1.648

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NH6737100

CHEMICAL NAME :: Ibogamine-18-carboxylic acid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-

CAS REGISTRY NUMBER :: 545-84-6

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H28-N2-O4

MOLECULAR WEIGHT :: 384.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 100 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 171,17,1986

COACRISTINE

voacristine

Voacangarin

20-hydroxy-12-methoxy-ibogamine-18-carboxylic acid methyl ester

Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-

Use of Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Synonyms