Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)

• 常用名: Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)
• 英文名: Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)
• CAS号: 545-84-6
• 分子量: 384.46900
• 密度: 1.32g/cm3
• 沸点: 542.9ºC at 760 mmHg
• 分子式: C₂₂H₂₈N₂O₄
• 熔点: N/A
• 闪点: 282.1ºC

用途

(–)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 g/ml).

名称

• 英文名: voacangarine

物理化学性质

• 密度: 1.32g/cm3
• 沸点: 542.9ºC at 760 mmHg
• 分子式: C₂₂H₂₈N₂O₄
• 分子量: 384.46900
• 闪点: 282.1ºC
• 精确质量: 384.20500
• PSA: 74.79000
• LogP: 2.17250
• InChIKey: OYMQKBZMKFJPMH-VJMPXSKLSA-N
• SMILES: COC(=O)C12CC3CC(C(C)O)C1N(CCc1c2[nH]c2ccc(OC)cc12)C3
• 折射率: 1.648
• 储存条件: -20°C，密闭，干燥

毒性和生态

英文别名

• COACRISTINE
• voacristine
• Voacangarin
• 20-hydroxy-12-methoxy-ibogamine-18-carboxylic acid methyl ester