N-Nitrosodiethylamine

Modify Date: 2024-01-02 19:14:18

N-Nitrosodiethylamine Structure
N-Nitrosodiethylamine structure
Common Name N-Nitrosodiethylamine
CAS Number 55-18-5 Molecular Weight 102.135
Density 0.9±0.1 g/cm3 Boiling Point 173.9±9.0 °C at 760 mmHg
Molecular Formula C4H10N2O Melting Point <25℃
MSDS Chinese USA Flash Point 59.0±18.7 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

 Use of N-Nitrosodiethylamine


N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

 Names

Name N-nitrosodiethylamine
Synonym More Synonyms

 N-Nitrosodiethylamine Biological Activity

Description N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 173.9±9.0 °C at 760 mmHg
Melting Point <25℃
Molecular Formula C4H10N2O
Molecular Weight 102.135
Flash Point 59.0±18.7 °C
Exact Mass 102.079315
PSA 32.67000
LogP 0.42
Vapour Pressure 1.7±0.3 mmHg at 25°C
Index of Refraction 1.442
Storage condition 2-8°C
Stability Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents, reducing agents.

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H301 + H311 + H331-H350-H370
Precautionary Statements P201-P260-P280-P301 + P310-P311
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T,F
Risk Phrases 45-22-39/23/24/25-23/24/25-11
Safety Phrases S53-S45-S36/37-S16
RIDADR UN 2810 6.1/PG 3
WGK Germany 3
RTECS IA3500000
Packaging Group III
Hazard Class 6.1(b)

 Synthetic Route

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 Synonyms

MFCD00013890
Ethanamine, N-ethyl-N-nitroso-
DENA
Nitrosodiethylamine
Diethylnitrosoamine
N,N-Diethylnitrosoamine
Diethylamine,N-nitroso
NDEA
Diethylnitrosamine
EINECS 200-226-1
N-nitroso-diethylamine
N,N-diethylnitrous amide
Ethanamine,N-ethyl-N-nitroso
N-Nitrosodiethylamine
N-Ethyl-N-nitrosoethanamine
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