(15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester

Modify Date: 2024-02-08 19:00:35

(15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester Structure
(15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester structure
Common Name (15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester
CAS Number 5523-37-5 Molecular Weight 350.41
Density N/A Boiling Point N/A
Molecular Formula C21H22N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester


Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity[1].

 Names

Name methyl (2S)-2-[(E)-1-oxobut-2-en-2-yl]-1,2,6,7,12,12b-hexahydroindolo[2,3-a]quinolizine-3-carboxylate
Synonym More Synonyms

  Biological Activity

Description Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity[1].
Related Catalog
In Vitro Vallesiachotamine induces G0/G1 arrest and increased the proportion of sub-G1 hypodiploid cells (at 11 μM and 22 μM) and this effect is not dependent on time of incubation. Vallesiachotamine acts by promoting G0/G1 cell cycle arrest, apoptosis and necrosis[1].
References

[1]. Paula R O Soares, et al. In vitro antiproliferative effects of the indole alkaloid vallesiachotamine on human melanoma cells. Paula R O Soares. 2012 Mar;35(3):565-71.  

 Chemical & Physical Properties

Molecular Formula C21H22N2O3
Molecular Weight 350.41
Exact Mass 350.16300
PSA 62.40000
LogP 3.22700

 Synonyms

18,19-Secoyohimban-19-oic acid,16,17,20,21-tetradehydro-16-formyl-,methyl ester,(15beta,16E)
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