Avarol

Modify Date: 2025-08-25 17:40:43

Avarol Structure
Avarol structure
 Common Name Avarol
CAS Number 55303-98-5 Molecular Weight 314.46200
Density 1.055g/cm3 Boiling Point 449.5ºC at 760 mmHg
Molecular Formula C21H30O2 Melting Point N/A
MSDS N/A Flash Point 200ºC

 Use of Avarol


Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling. Avarl also acts as a competitive AChE inhibitor which are non-hepatotoxic and neuroprotective agents for Alzheimer's disease.

 Names

Name 2-[[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.055g/cm3
Boiling Point 449.5ºC at 760 mmHg
Molecular Formula C21H30O2
Molecular Weight 314.46200
Flash Point 200ºC
Exact Mass 314.22500
PSA 40.46000
LogP 5.43910
Index of Refraction 1.552
InChIKey JSPUCPNQXKTYRO-LWILDLIXSA-N
SMILES CC1=CCCC2C1(C)CCC(C)C2(C)Cc1cc(O)ccc1O

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ9026700
CHEMICAL NAME :
1,4-Benzenediol, 2-((1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl- 1-naphthalenyl) methyl)-, (1R-(1-alpha,2-beta,4a-beta,8a-alpha))-
CAS REGISTRY NUMBER :
55303-98-5
LAST UPDATED :
199406
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C21-H30-O2
MOLECULAR WEIGHT :
314.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
269 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Cells - not otherwise specified
DOSE/DURATION :
3800 nmol/L
REFERENCE :
EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 22,473,1986

 Synthetic Route

 Synonyms

Avarol
2-{[(1r,2s,4as,8as)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl]methyl}benzene-1,4-diol
(1R-(1alpha,2beta,4abeta,8abeta))-2-((1,2,3,4,4a,7,8,8a-Octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl)-1,4-benzenediol
Avrol
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Avarol suppliers

Avarol price

Related Compounds: More...
Avarol F
130203-72-4
Avarol-diacetat
61187-44-8
avarol monoacetate
122143-92-4
4-Chloro-6-ethyl-2-(3-methylcyclohexyl)pyrimidine
1249036-44-9
5-Chloro-4-fluoro-2-(propan-2-yloxy)aniline
1466329-28-1
1-{4-[1-methyl-3-(propan-2-yl)-1H-pyrazol-4-yl]phenyl}ethan-1-amine
1489991-47-0
4-[1-methyl-3-(propan-2-yl)-1H-pyrazol-4-yl]benzaldehyde
1465463-19-7
2-(Chloromethyl)-4-(methoxymethyl)oxazole
1381778-95-5
2-Furansulfonamide, 5-(aminomethyl)-N-(1-methylethyl)-N-(2,2,2-trifluoroethyl)-
1480013-07-7
Methyl 2-[[2-(dimethylamino)ethyl]methylamino]-4-benzoxazolecarboxylate
1014712-79-8
1-(Sec-butyl)-1H-1,2,4-triazol-3-amine
1178035-01-2
2-(Pyrazin-2-yl)propan-1-amine
1344261-52-4
3-(Thiazol-2-yl)propanenitrile
1517989-75-1
Chemsrc provides Avarol(CAS#:55303-98-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Avarol are included as well.>> amp version: Avarol

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved