Avarol

• 常用名: Avarol
• 英文名: Avarol
• CAS号: 55303-98-5
• 分子量: 314.46200
• 密度: 1.055g/cm3
• 沸点: 449.5ºC at 760 mmHg
• 分子式: C₂₁H₃₀O₂
• 熔点: N/A
• 闪点: 200ºC

Avarol用途

Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling. Avarl also acts as a competitive AChE inhibitor which are non-hepatotoxic and neuroprotective agents for Alzheimer's disease.

Avarol名称

• 英文名: 2-[[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol

Avarol物理化学性质

• 密度: 1.055g/cm3
• 沸点: 449.5ºC at 760 mmHg
• 分子式: C₂₁H₃₀O₂
• 分子量: 314.46200
• 闪点: 200ºC
• 精确质量: 314.22500
• PSA: 40.46000
• LogP: 5.43910
• InChIKey: JSPUCPNQXKTYRO-LWILDLIXSA-N
• SMILES: CC1=CCCC2C1(C)CCC(C)C2(C)Cc1cc(O)ccc1O
• 折射率: 1.552

Avarol毒性和生态

Avarol靶点实验

查看更多实验

实验名称：Neurotoxicity in human SH-SY5Y cells assessed as decrease in cell viability at 25 to ... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3868669

实验名称：Inhibition of COX2 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL1008495

实验名称：Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia co... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL3860325

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Cytotoxicity against human phytohemagglutininin-stimulated PBMC cells assessed as gro... 来源：ChEMBL 靶标：PBMC External Id：CHEMBL1102855

实验名称：Cytotoxicity against human PBMC cells by MTT assay 来源：ChEMBL 靶标：PBMC External Id：CHEMBL1102854

实验名称：Cytotoxicity against human K562 cells by MTT assay 来源：ChEMBL 靶标：K562 External Id：CHEMBL1102853

实验名称：Cytotoxicity against human Fem-X cells assessed as decrease in total cellular protein... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1102852

实验名称：Cytotoxicity against human HeLa cells assessed as decrease in total cellular protein ... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL1102851

实验名称：Antimicrobial activity against Micrococcus luteus DSM 348 after 18 hrs by twofold ser... 来源：ChEMBL 靶标：Micrococcus luteus External Id：CHEMBL1009527

共42条，当前第1页，共5页

1

2

3

4

5

Avarol英文别名

• Avarol
• 2-{[(1r,2s,4as,8as)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl]methyl}benzene-1,4-diol
• (1R-(1alpha,2beta,4abeta,8abeta))-2-((1,2,3,4,4a,7,8,8a-Octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl)-1,4-benzenediol
• Avrol