2,4-Dichloroaniline

Modify Date: 2026-07-19 18:18:30

2,4-Dichloroaniline Structure
2,4-Dichloroaniline structure
Common Name 2,4-Dichloroaniline
CAS Number 554-00-7 Molecular Weight 162.017
Density 1.4±0.1 g/cm3 Boiling Point 242.1±20.0 °C at 760 mmHg
Molecular Formula C6H5Cl2N Melting Point 59-62 °C(lit.)
MSDS Chinese USA Flash Point 100.2±21.8 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2,4-dichloroaniline
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.4±0.1 g/cm3
Boiling Point 242.1±20.0 °C at 760 mmHg
Melting Point 59-62 °C(lit.)
Molecular Formula C6H5Cl2N
Molecular Weight 162.017
Flash Point 100.2±21.8 °C
Exact Mass 160.979904
PSA 26.02000
LogP 2.74
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.614
InChIKey KQCMTOWTPBNWDB-UHFFFAOYSA-N
SMILES Nc1ccc(Cl)cc1Cl
Water Solubility Insoluble,

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BX2600000
CHEMICAL NAME :
Aniline, 2,4-dichloro-
CAS REGISTRY NUMBER :
554-00-7
BEILSTEIN REFERENCE NO. :
0386422
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C6-H5-Cl2-N
MOLECULAR WEIGHT :
162.02
WISWESSER LINE NOTATION :
ZR BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
113 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions Lungs, Thorax, or Respiration - cyanosis Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 72,241,1913

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301-H311-H331-H373-H410
Precautionary Statements P261-P273-P280-P301 + P310-P311-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R23/24/25;R33;R50/53
Safety Phrases S28-S36/37-S45-S60-S61-S28A
RIDADR UN 3442 6.1/PG 2
WGK Germany 3
RTECS BX2600000
Packaging Group II
Hazard Class 6.1
HS Code 2921499090

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2921420090
Summary HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles26

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Biodegradation of 2-chloroaniline, 3-chloroaniline, and 4-chloroaniline by a novel strain Delftia tsuruhatensis H1.

J. Hazard. Mater. 179(1-3) , 875-82, (2010)

A new strain Delftia tsuruhatensis H1 able to degrade several chloroanilines (CAs) as individual compounds or a mixture was isolated from a CA-degrading mixed bacterial culture. The isolated strain co...

Sensitivity of muscle satellite cells to pollutants: an in vitro and in vivo comparative approach.

Aquat. Toxicol. 53(3-4) , 247-63, (2001)

Muscle satellite cells from rainbow trout were exposed in vitro to increasing concentrations of different xenobiotics: copper, dichloroaniline, prochloraz, nonyl-phenol polyethexylate. Mortality and p...

Expression of delayed cell death (DCD) in the progeny of fish cells surviving 2,4-dichloroaniline (2,4-DCA) exposure.

Aquat. Toxicol. 63(3) , 207-19, (2003)

Interest in and concern for the quality of the environment has prompted a great deal of research into methods of measuring and assessing changes in it. One problem of major interest is that of increas...

 2,4-DichloroanilineBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2,4-Dichloroaniline
2,4-di-Cl-aniline
2,4-Dichloro Aniline
1-Amino-2,4-dichlorobenzene
2,4-Dichloranilin
2,4-dichloro
EINECS 209-057-8
2,4-DCA
AURORA KA-688
2,4-dichloro-anilin
1,5-dichloro-4-aminobenzene
o,p-Dichloroaniline
2,4-dichloro-aniline
4-Dichloroaniline
MFCD00007661
2,4-dichloro-phenylamine

 2,4-Dichloroaniline | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the downstream products of 2,4-dichloroaniline?
A: Related downstream products(CAS) of 2,4-dichloroaniline: 111992-18-8;5446-18-4;37680-66-3;50-84-0;3698-83-7;41464-40-8;34033-44-8;32598-10-0;35113-88-3;35113-90-7.
Q: What is the boiling point of 2,4-dichloroaniline?
A: Boiling point of 2,4-dichloroaniline is 242.1±20.0 °C at 760 mmHg.
Q: What are the upstream materials of 2,4-dichloroaniline?
A: Related upstream materials(CAS) of 2,4-dichloroaniline: 36984-15-3;106-47-8;611-06-3;13665-50-4;296778-52-4;1965-25-9;120-83-2;116278-63-8;6975-29-7.
Q: What is the CAS number of 2,4-dichloroaniline?
A: CAS number of 2,4-dichloroaniline is 554-00-7.
Q: What is the molecular formula of 2,4-dichloroaniline?
A: Molecular formula of 2,4-dichloroaniline is C6H5Cl2N.
Q: What is the InChIKey of 2,4-dichloroaniline?
A: InChIKey of 2,4-dichloroaniline is KQCMTOWTPBNWDB-UHFFFAOYSA-N.
Q: What is the molecular weight of 2,4-dichloroaniline?
A: Molecular weight of 2,4-dichloroaniline is 162.017.
Q: What English synonyms does 2,4-dichloroaniline have?
A: English synonyms of 2,4-dichloroaniline: 2,4-Dichloroaniline, 2,4-di-Cl-aniline, 2,4-Dichloro Aniline, 1-Amino-2,4-dichlorobenzene, 2,4-Dichloranilin, 2,4-dichloro, EINECS 209-057-8, 2,4-DCA, AURORA KA-688, 2,4-dichloro-anilin, 1,5-dichloro-4-aminobenzene, o,p-Dichloroaniline, 2,4-dichloro-aniline, 4-Dichloroaniline, MFCD00007661, 2,4-dichloro-phenylamine.
Q: How is the water solubility of 2,4-dichloroaniline?
A: Water solubility of 2,4-dichloroaniline: Insoluble,.
Q: What is the safety information for 2,4-dichloroaniline?
A: Safety information for 2,4-dichloroaniline: S28-S36/37-S45-S60-S61-S28A.

 2,4-Dichloroanilinefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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