mollugin

Modify Date: 2024-01-04 18:44:08

mollugin structure	Common Name	mollugin
	CAS Number	55481-88-4	Molecular Weight	284.306
	Density	1.2±0.1 g/cm3	Boiling Point	453.2±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₆O₄	Melting Point	132-134ºC
	MSDS	Chinese USA	Flash Point	167.5±22.2 °C

Use of mollugin

Mollugin is a major bioactive component isolated from Rubia cordifolia L.. Mollugin has an anti-cancer therapeutic effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway [1][2].

Name	mollugin
Synonym	More Synonyms

Description	Mollugin is a major bioactive component isolated from Rubia cordifolia L.. Mollugin has an anti-cancer therapeutic effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway [1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Wang Z, et al. Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation. Int J Mol Sci. 2017 Jul 26;18(8). [2]. Moon SH, et al. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway. Arch Pharm Res. 2017 Nov;40(11):1328-1335.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Wang Z, et al. Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation. Int J Mol Sci. 2017 Jul 26;18(8).

[2]. Moon SH, et al. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway. Arch Pharm Res. 2017 Nov;40(11):1328-1335.

Density	1.2±0.1 g/cm3
Boiling Point	453.2±45.0 °C at 760 mmHg
Melting Point	132-134ºC
Molecular Formula	C₁₇H₁₆O₄
Molecular Weight	284.306
Flash Point	167.5±22.2 °C
Exact Mass	284.104858
PSA	55.76000
LogP	5.16
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.619

Hazard Codes	Xi
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
HS Code	29329990

Precursor 7
CAS#:873531-15-8 1,4-dimethoxy-3... CAS#:60657-93-4 Dihydromollugin CAS#:83575-14-8 methyl 1,4-diox... CAS#:107-86-8 3-Methyl-2-butenal
CAS#:77060-74-3 Methyl 1,4-dihy... CAS#:104108-29-4 prenyltributyltin CAS#:78570-30-6 2-methoxycarbon...
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