mollugin

Modify Date: 2024-01-04 18:44:08

mollugin Structure
mollugin structure
 Common Name mollugin
CAS Number 55481-88-4 Molecular Weight 284.306
Density 1.2±0.1 g/cm3 Boiling Point 453.2±45.0 °C at 760 mmHg
Molecular Formula C17H16O4 Melting Point 132-134ºC
MSDS Chinese USA Flash Point 167.5±22.2 °C

 Use of mollugin


Mollugin is a major bioactive component isolated from Rubia cordifolia L.. Mollugin has an anti-cancer therapeutic effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway [1][2].

 Names

Name mollugin
Synonym More Synonyms

 mollugin Biological Activity

Description Mollugin is a major bioactive component isolated from Rubia cordifolia L.. Mollugin has an anti-cancer therapeutic effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway [1][2].
Related Catalog
References

[1]. Wang Z, et al. Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation. Int J Mol Sci. 2017 Jul 26;18(8).

[2]. Moon SH, et al. Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway. Arch Pharm Res. 2017 Nov;40(11):1328-1335.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 453.2±45.0 °C at 760 mmHg
Melting Point 132-134ºC
Molecular Formula C17H16O4
Molecular Weight 284.306
Flash Point 167.5±22.2 °C
Exact Mass 284.104858
PSA 55.76000
LogP 5.16
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.619

 Safety Information

Hazard Codes Xi
Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 29329990

 Synthetic Route

 Synonyms

Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
5-Carbomethoxy-6-hydroxy-2,2-dimethyl-2H-naphtho<1,2-b>-pyran
2H-Naphtho[1,2-b]pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester
Rubimaillin
Mollugin/rubiMaillin
6-hydroxy-2,2-dimethyl-,methylester
mollugin
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Chemsrc provides mollugin(CAS#:55481-88-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of mollugin are included as well.>> amp version: mollugin

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