2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol

Modify Date: 2024-01-02 16:43:10

2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol Structure
2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol structure
Common Name 2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol
CAS Number 55489-58-2 Molecular Weight 240.296
Density 1.1±0.1 g/cm3 Boiling Point 358.0±27.0 °C at 760 mmHg
Molecular Formula C13H20O4 Melting Point N/A
MSDS N/A Flash Point 170.3±23.7 °C

 Use of 2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol


Triethylene glycol monobenzyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Triethylene Glycol Monobenzyl Ether
Synonym More Synonyms

 2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol Biological Activity

Description Triethylene glycol monobenzyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 358.0±27.0 °C at 760 mmHg
Molecular Formula C13H20O4
Molecular Weight 240.296
Flash Point 170.3±23.7 °C
Exact Mass 240.136154
PSA 47.92000
LogP 0.54
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.506

 Safety Information

Hazard Codes Xi
HS Code 2909499000

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

2-[2-(2-phenylmethoxyethoxy)ethoxy]ethanol
Ethanol, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-
MFCD02093556
2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol