Dapsone D8
Modify Date: 2024-01-04 14:12:11
Dapsone D8 structure
|
Common Name | Dapsone D8 | ||
|---|---|---|---|---|
| CAS Number | 557794-38-4 | Molecular Weight | 248.30100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H4D8N2O2S | Melting Point | 164-167°C | |
| MSDS | N/A | Flash Point | N/A | |
Use of Dapsone D8Dapsone D8 is a deuterium labeled Dapsone. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved. |
| Name | 4-(4-amino-2,3,5,6-tetradeuteriophenyl)sulfonyl-2,3,5,6-tetradeuterioaniline |
|---|---|
| Synonym | More Synonyms |
| Description | Dapsone D8 is a deuterium labeled Dapsone. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved. |
|---|---|
| Related Catalog |
| Melting Point | 164-167°C |
|---|---|
| Molecular Formula | C12H4D8N2O2S |
| Molecular Weight | 248.30100 |
| Exact Mass | 248.06200 |
| PSA | 94.56000 |
| LogP | 3.92700 |
| Storage condition | -20°C Freezer |
|
~94%
Dapsone D8 CAS#:557794-38-4 |
| Literature: WAKO PURE CHEMICAL INDUSTRIES, LTD. Patent: US2008/45724 A1, 2008 ; Location in patent: Page/Page column 18 ; |
|
~%
Dapsone D8 CAS#:557794-38-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, # 2 p. 107 - 114 |
|
~%
Dapsone D8 CAS#:557794-38-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, # 2 p. 107 - 114 |
|
~%
Dapsone D8 CAS#:557794-38-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, # 2 p. 107 - 114 |
|
~80%
Dapsone D8 CAS#:557794-38-4 |
| Literature: Gannett, Peter M.; Johnson II, Edward M.; Grimes, Michael A.; Myers, Alan L.; Deavers III, Robert E.; Tracy, Timothy S. Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, # 2 p. 107 - 114 |
![N-[4-(4-acetamido-2,3,5,6-tetradeuteriophenyl)sulfonyl-2,3,5,6-tetradeuteriophenyl]acetamide structure](https://www.chemsrc.com/caspic/272/557794-37-3.png)
| deuterated 4,4'-diaminodiphenylsulfone |
| 4,4 inverted exclamation mark-Sulfonylbisbenzeneamine-D8 |
| 4,4'-Sulfonylbis-benzen-2,3,5,6-d4-amine |