Buflomedil

Modify Date: 2024-01-03 16:05:31

Buflomedil structure	Common Name	Buflomedil
	CAS Number	55837-25-7	Molecular Weight	307.385
	Density	1.1±0.1 g/cm3	Boiling Point	454.5±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₅NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	228.7±28.7 °C

Use of Buflomedil

Buflomedil is an orally active vasoactive agent. Buflomedil is an α1-, α2-adrenolytic compound. Buflomedil can be used for research of cardiovascular disease, such as peripheral vascular disease[1][2].

Name	Buflomedil
Synonym	More Synonyms

Description	Buflomedil is an orally active vasoactive agent. Buflomedil is an α1-, α2-adrenolytic compound. Buflomedil can be used for research of cardiovascular disease, such as peripheral vascular disease[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. de Backer TL, et al. Buflomedil for intermittent claudication. Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD000988. [2]. Limbs International Medicinal Buflomedil (LIMB) Study Group; Leizorovicz A, Becker F. Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study. Circulation. 2008 Feb 12;117(6):816-22.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

References

[1]. de Backer TL, et al. Buflomedil for intermittent claudication. Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD000988.

[2]. Limbs International Medicinal Buflomedil (LIMB) Study Group; Leizorovicz A, Becker F. Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study. Circulation. 2008 Feb 12;117(6):816-22.

Density	1.1±0.1 g/cm3
Boiling Point	454.5±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₂₅NO₄
Molecular Weight	307.385
Flash Point	228.7±28.7 °C
Exact Mass	307.178345
PSA	48.00000
LogP	2.46
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.520

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EL9885000

CHEMICAL NAME :: 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-

CAS REGISTRY NUMBER :: 55837-25-7

LAST UPDATED :: 199109

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H25-N-O4

MOLECULAR WEIGHT :: 307.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 1080 umol/L

REFERENCE :: TIVIEQ Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 4,751,1990

Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	26-36
WGK Germany	3
RTECS	EL9885000
HS Code	29339990

HS Code	29339990

4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone

1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-

Buflomedil

BufluomedilHcl

EINECS 259-851-3

AURORA KA-850

4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one

4-pyrrolidin-1-yl-1-[2,4,6-tris(methyloxy)phenyl]butan-1-one

4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one

MFCD00242740

4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-on

(2,4,6-Trimethoxyphenyl) (3-Pyrrolidinopropyl) Ketone

Buflomedil

Use of Buflomedil

Names

Buflomedil Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

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Synonyms