4-Hydroxyderricin

Modify Date: 2024-01-02 11:20:30

4-Hydroxyderricin Structure
4-Hydroxyderricin structure
Common Name 4-Hydroxyderricin
CAS Number 55912-03-3 Molecular Weight 338.39700
Density 1.181g/cm3 Boiling Point 542ºC at 760mmHg
Molecular Formula C21H22O4 Melting Point 136-137℃
MSDS N/A Flash Point 190.8ºC

 Use of 4-Hydroxyderricin


4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].

 Names

Name (E)-1-[2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
Synonym More Synonyms

 4-Hydroxyderricin Biological Activity

Description 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].
Target

IC50: 3.43 μM (MAO-B)[1]

References

[1]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.

 Chemical & Physical Properties

Density 1.181g/cm3
Boiling Point 542ºC at 760mmHg
Melting Point 136-137℃
Molecular Formula C21H22O4
Molecular Weight 338.39700
Flash Point 190.8ºC
Exact Mass 338.15200
PSA 66.76000
LogP 4.51120
Index of Refraction 1.622
Storage condition 2-8℃

 Synonyms

HMS2195D24
4-Hydroxydervicin
4-hydroxyionchocarpin
4-Hydroxyderricin
Top Suppliers:I want be here


Get all suppliers and price by the below link:

4-Hydroxyderricin suppliers

4-Hydroxyderricin price