Felypressin
Felypressin structure
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Common Name | Felypressin | ||
|---|---|---|---|---|
| CAS Number | 56-59-7 | Molecular Weight | 1040.219 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1571.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C46H65N13O11S2 | Melting Point | 254-257 °C | |
| MSDS | Chinese USA | Flash Point | 904.1±34.3 °C | |
Use of FelypressinFelypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | felypressin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Felypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures. |
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| Related Catalog | |
| References |
[2]. Cecanho R et al. Cardiovascular effects of felypressin. Anesth Prog. 2006 Winter;53(4):119-25. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1571.3±65.0 °C at 760 mmHg |
| Melting Point | 254-257 °C |
| Molecular Formula | C46H65N13O11S2 |
| Molecular Weight | 1040.219 |
| Flash Point | 904.1±34.3 °C |
| Exact Mass | 1039.436768 |
| PSA | 455.92000 |
| LogP | -5.00 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.574 |
| InChIKey | SFKQVVDKFKYTNA-XDYZDBQGSA-N |
| SMILES | NCCCCC(NC(=O)C1CCCN1C(=O)C1CSSCC(N)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa.
J. Pharm. Sci. 103(7) , 2053-61, (2014) The pH partition theory proposes a correlation between fraction of unionized drug substance and permeability. The aim of this study was to compare the permeability of metoprolol and mannitol in ex viv... |
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Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.
Cochrane Database Syst. Rev. 12 , CD009742, (2014) Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage post... |
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Octopus, which owns the most advanced brain in invertebrates, has two members of vasopressin/oxytocin superfamily as in vertebrates.
Regul. Pept. 115(2) , 139-49, (2003) A novel member of the vasopressin/oxytocin superfamily, octopressin (OP), has been isolated from Octopus vulgaris. Since another peptide of this superfamily, cephalotocin (CT), was isolated from the s... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (2-L-Phenylalanine)-8-lysinevasopressin |
| Felypressine |
| M.W. 1040.22 C46H65N13O11S2 |
| Felypressin Acetate |
| 2-(Phenylalanine)-8-lysine vasopressin |
| felypressin |
| [PHE2,LYS8]-VASOPRESSIN |
| 2-(L-Phenylalanine)-8-L-lysinevasopressin |
| Octapressin |
| MFCD00868221 |
| PLV-2 |
| 2-(phenylalanine)-8-lyine vasopression |
| Phelypressin |
| L-Cysteinyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1®6)disulfide |
| EINECS 200-282-7 |
| 1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-lysylglycinamide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for felypressin? |
| A: Safety information for felypressin: S24/25. |
| Q: What is the molecular weight of felypressin? |
| A: Molecular weight of felypressin is 1040.219. |
| Q: What is the SMILES notation of felypressin? |
| A: SMILES notation of felypressin is NCCCCC(NC(=O)C1CCCN1C(=O)C1CSSCC(N)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N1)C(=O)NCC(N)=O. |
| Q: What are the uses of felypressin? |
| A: Main uses of felypressin: Felypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures. |
| Q: What is the InChIKey of felypressin? |
| A: InChIKey of felypressin is SFKQVVDKFKYTNA-XDYZDBQGSA-N. |
| Q: What is the CAS number of felypressin? |
| A: CAS number of felypressin is 56-59-7. |
| Q: What is the English name of felypressin? |
| A: The English name of felypressin is felypressin. |
| Q: What is the melting point of felypressin? |
| A: Melting point of felypressin is 254-257 °C. |
| Q: What is the polar surface area (PSA) of felypressin? |
| A: Polar surface area (PSA) of felypressin is 455.92000. |
| Q: What is the LogP of felypressin? |
| A: LogP of felypressin is -5.00. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |