Felypressin

Modify Date: 2024-01-02 08:08:06

Felypressin Structure
Felypressin structure
 Common Name Felypressin
CAS Number 56-59-7 Molecular Weight 1040.219
Density 1.3±0.1 g/cm3 Boiling Point 1571.3±65.0 °C at 760 mmHg
Molecular Formula C46H65N13O11S2 Melting Point 254-257 °C
MSDS Chinese USA Flash Point 904.1±34.3 °C

 Use of Felypressin


Felypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures.

 Names

Name felypressin
Synonym More Synonyms

 Felypressin Biological Activity

Description Felypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures.
Related Catalog
References

[1]. Bronzo AL et al. Felypressin increases blood pressure during dental procedures in hypertensive patients. Arq Bras Cardiol. 2012 Aug;99(2):724-31.

[2]. Cecanho R et al. Cardiovascular effects of felypressin. Anesth Prog. 2006 Winter;53(4):119-25.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1571.3±65.0 °C at 760 mmHg
Melting Point 254-257 °C
Molecular Formula C46H65N13O11S2
Molecular Weight 1040.219
Flash Point 904.1±34.3 °C
Exact Mass 1039.436768
PSA 455.92000
LogP -5.00
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.574

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S24/25
RIDADR NONH for all modes of transport

 Articles27

More Articles
Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa.

J. Pharm. Sci. 103(7) , 2053-61, (2014)

The pH partition theory proposes a correlation between fraction of unionized drug substance and permeability. The aim of this study was to compare the permeability of metoprolol and mannitol in ex viv...

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.

Cochrane Database Syst. Rev. 12 , CD009742, (2014)

Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage post...

Octopus, which owns the most advanced brain in invertebrates, has two members of vasopressin/oxytocin superfamily as in vertebrates.

Regul. Pept. 115(2) , 139-49, (2003)

A novel member of the vasopressin/oxytocin superfamily, octopressin (OP), has been isolated from Octopus vulgaris. Since another peptide of this superfamily, cephalotocin (CT), was isolated from the s...

 Synonyms

(2-L-Phenylalanine)-8-lysinevasopressin
Glycinamide, 1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-6,9,12,15,18-pentaoxo-13,16-bis(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-lysyl-
Felypressine
M.W. 1040.22 C46H65N13O11S2
Felypressin Acetate
2-(Phenylalanine)-8-lysine vasopressin
felypressin
[PHE2,LYS8]-VASOPRESSIN
2-(L-Phenylalanine)-8-L-lysinevasopressin
Octapressin
MFCD00868221
PLV-2
2-(phenylalanine)-8-lyine vasopression
Phelypressin
L-Cysteinyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1®6)disulfide
EINECS 200-282-7
1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-lysylglycinamide
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