18-Hydroxycorticosterone

Modify Date: 2024-01-11 20:02:53

18-Hydroxycorticosterone Structure
18-Hydroxycorticosterone structure
Common Name 18-Hydroxycorticosterone
CAS Number 561-65-9 Molecular Weight 362.46000
Density N/A Boiling Point N/A
Molecular Formula C21H30O5 Melting Point N/A
MSDS USA Flash Point 2 °C - closed cup (lit.)

 Use of 18-Hydroxycorticosterone


18-Hydroxycorticosterone is a corticosteroid and a derivative of corticosterone, which can lead to serious electrolyte imbalances.

 Names

Name 18-hydroxycorticosterone
Synonym More Synonyms

 18-Hydroxycorticosterone Biological Activity

Description 18-Hydroxycorticosterone is a corticosteroid and a derivative of corticosterone, which can lead to serious electrolyte imbalances.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Molecular Formula C21H30O5
Molecular Weight 362.46000
Flash Point 2 °C - closed cup (lit.)
Exact Mass 362.20900
PSA 94.83000
LogP 1.63910

 Safety Information

RIDADR NONH for all modes of transport

 Articles34

More Articles
Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).

J. Med. Chem. 53 , 1712-25, (2010)

Reducing aldosterone action is beneficial in various major diseases such as heart failure. Currently, this is achieved with mineralocorticoid receptor antagonists, however, aldosterone synthase (CYP11...

["High pouch output" syndrome. Role of mineralocorticoid diagnosis after restorative proctocolectomy].

Chirurg. 72(12) , 1446-52, (2001)

The two-phase restorative proctocolectomy is the treatment of choice for surgical therapy of the familial adenomatous polyposis (FAP) and also for the ulcerative colitis (UC). Besides the well-known c...

Dose-dependence of the effects of corticosterone and the non-glucocorticoid, 18-hydroxycorticosterone, on the brush-border Na+/K+ exchanger.

Endocr. Res. 24(3-4) , 601-5, (1998)

Up to now, only glucocorticoids were thought to act on the renal proximal Na+/H+ exchanger. Using fluorimetric techniques we studied the kinetics of Na+/H+ exchange in brush border vesicles from ADX r...

 Synonyms

(8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
18-Hydroxy Corticosterone
EINECS 209-221-9
11beta,18,21-Trihydroxypregn-4-ene-3,20-dione