parapenzolate bromide

Modify Date: 2024-01-11 12:04:31

parapenzolate bromide Structure
parapenzolate bromide structure
Common Name parapenzolate bromide
CAS Number 5634-41-3 Molecular Weight 420.34000
Density N/A Boiling Point N/A
Molecular Formula C21H26BrNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of parapenzolate bromide


Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent[1][2].

 Names

Name (1,1-dimethylpiperidin-1-ium-4-yl) 2-hydroxy-2,2-diphenylacetate,bromide
Synonym More Synonyms

 parapenzolate bromide Biological Activity

Description Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent[1][2].
Related Catalog
In Vivo Parapenzolate bromide (10 mg/kg, p.o. or i.v.) shows a significant analgesic effect in mice[1]. Parapenzolate bromide (0.5 mg/kg, i.v.) exhibits a spasmolytic activity in isolated gall bladder from guinea pigs[2]. Animal Model: Mice[1] Dosage: 10 mg/kg Administration: Oral administration (p.o.) or intravenous injection (i.v.) Result: Prolonged the time until death in convulsive mice. Animal Model: Guinea pigs[2] Dosage: 0.5 mg/kg Administration: Intravenous injection (i.v.) Result: Antagonized contractions induced by acetylcholine (100 μg/kg, i.v.)
References

[1]. Paris, J., et al. Effect of parapenzolate bromide on the contractility of the gall bladder and sphincter of Oddi. Therapie (1968), 23(3), 609-18.

[2]. Ishimura Yasuko, et al. Pharmacological studies on parapenzolate bromide. 1. Pharmacological studies. Shikoku Igaku Zasshi (1970), 26(1), 43-51.

 Chemical & Physical Properties

Molecular Formula C21H26BrNO3
Molecular Weight 420.34000
Exact Mass 419.11000
PSA 46.53000

 Synthetic Route

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parapenzolate bromide Structure

parapenzolate b...

CAS#:5634-41-3

Literature: Coan et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 3701

~%

parapenzolate bromide Structure

parapenzolate b...

CAS#:5634-41-3

Literature: Coan et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 3701

~%

parapenzolate bromide Structure

parapenzolate b...

CAS#:5634-41-3

Literature: Coan et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 3701

~%

parapenzolate bromide Structure

parapenzolate b...

CAS#:5634-41-3

Literature: Coan et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 3701

~%

parapenzolate bromide Structure

parapenzolate b...

CAS#:5634-41-3

Literature: Coan et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 3701

 Synonyms

Bromuro de parapenzolato
Bromure de parapenzolate
Parapenzolate bromide
Parapenzolati bromidum
Parapenzolatbromid
4-benziloyloxy-1,1-dimethyl-piperidinium,bromide
4-[2-hydroxy(diphenyl)acetoxy]-1,1-dimethylpiperidinium bromide
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