11-cis Retinal

Modify Date: 2025-08-25 14:06:36

11-cis Retinal Structure
11-cis Retinal structure
Common Name 11-cis Retinal
CAS Number 564-87-4 Molecular Weight 284.44
Density 0.948g/cm3 Boiling Point 421.4ºC at 760 mmHg
Molecular Formula C20H28O Melting Point N/A
MSDS N/A Flash Point 205.4ºC

 Use of 11-cis Retinal


11-cis-Retinal is a chromophore linkes via a Schiff base to the lysine residue of opsin[1].

 Names

Name 11-cis-retinal
Synonym More Synonyms

 11-cis Retinal Biological Activity

Description 11-cis-Retinal is a chromophore linkes via a Schiff base to the lysine residue of opsin[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Hara M, et al. PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle. Cell Rep. 2023 Feb 8;42(2):112091.  

 Chemical & Physical Properties

Density 0.948g/cm3
Boiling Point 421.4ºC at 760 mmHg
Molecular Formula C20H28O
Molecular Weight 284.44
Flash Point 205.4ºC
Exact Mass 284.21400
PSA 17.07000
LogP 5.71690
Index of Refraction 1.54
InChIKey NCYCYZXNIZJOKI-IOUUIBBYSA-N
SMILES CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=O

 Synthetic Route

 11-cis RetinalBioassay

View more

Name: Agonist activity at bovine rhodopsin assessed as opsin mediated cognate G protein tra...
Source: ChEMBL
Target: Rhodopsin
External Id: CHEMBL1769973
Name: Experimentally measured binding affinity data (Kd) for protein-ligand complexes deriv...
Source: Shanghai Institute of Organic Chemistry
Target: N/A
External Id: PDBbind-Kd for protein-ligand complexes
Name: Inverse agonist activity at human red cone opsin expressed in COS1 cells assessed as ...
Source: ChEMBL
Target: Long-wave-sensitive opsin 1
External Id: CHEMBL1953565
Name: Upregulation of HA-tagged rhodopsin P23H expression in HEK293 cell surface by ELISA
Source: ChEMBL
Target: HEK293
External Id: CHEMBL1251197
Name: Cytotoxicity against HEK293 cells by WST-1 assay
Source: ChEMBL
Target: HEK293
External Id: CHEMBL1251196
Name: Induction of subcellular localization of HA-tagged human rhodopsin P23H mutant on HEK...
Source: ChEMBL
Target: Rhodopsin
External Id: CHEMBL1251195
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 Synonyms

11-cis-Vitamin A aldehyde
cis-11-retinal
11-cis-Retinal
Neoretinene b
11-cis-Retinene
RHODOPSIN
9-cis-retinal
cis-Retinal
11-cis-Retinaldehyde
(2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenal
11-Z-retinal
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