CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UF0700000
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CHEMICAL NAME :
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Propionic acid, 2,3-dichloro-
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CAS REGISTRY NUMBER :
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565-64-0
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BEILSTEIN REFERENCE NO. :
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1721427
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C3-H4-Cl2-O2
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MOLECULAR WEIGHT :
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142.97
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WISWESSER LINE NOTATION :
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QVYG1G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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289 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema
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REFERENCE :
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WATRAG Water Research. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 0BW, UK) V.1- 1967- Volume(issue)/page/year: 24,661,1990
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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400 mg/kg
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TOXIC EFFECTS :
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Skin and Appendages - primary irritation (after topical exposure)
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REFERENCE :
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AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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588 mg/kg/28D-C
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TOXIC EFFECTS :
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Cardiac - changes in heart weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
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REFERENCE :
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WATRAG Water Research. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 0BW, UK) V.1- 1967- Volume(issue)/page/year: 24,661,1990
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