cholest-5-en-3β,7α-diol

Modify Date: 2025-09-12 11:48:15

cholest-5-en-3β,7α-diol structure	Common Name	cholest-5-en-3β,7α-diol
	CAS Number	566-26-7	Molecular Weight	402.65300
	Density	1.03g/cm3	Boiling Point	515.3ºC at 760mmHg
	Molecular Formula	C₂₇H₄₆O₂	Melting Point	168-170ºC
	MSDS	N/A	Flash Point	214.7ºC

Use of cholest-5-en-3β,7α-diol

7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2].

Name	7α-hydroxycholesterol
Synonym	More Synonyms

Description	7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Ferderbar S, et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. Diabetes Metab Res Rev. 2007 Jan;23(1):35-42. [2]. Kitano S, et al. Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). Anal Chim Acta. 2007 Feb 28;585(1):86-93.

Description

7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Ferderbar S, et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. Diabetes Metab Res Rev. 2007 Jan;23(1):35-42.

[2]. Kitano S, et al. Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). Anal Chim Acta. 2007 Feb 28;585(1):86-93.

Density	1.03g/cm3
Boiling Point	515.3ºC at 760mmHg
Melting Point	168-170ºC
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.65300
Flash Point	214.7ºC
Exact Mass	402.35000
PSA	40.46000
LogP	6.35950
Index of Refraction	1.536
InChIKey	OYXZMSRRJOYLLO-RVOWOUOISA-N
SMILES	CC(C)CCCC(C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C
Storage condition	-20°C

Precursor 0
DownStream 4
CAS#:566-93-8 Cholesta-4,6-di... CAS#:3862-25-7 7α-Hydroxy-4-ch... CAS#:80-97-7 Dihydrocholesterol CAS#:13095-38-0 Cholesta-2,4,6-...

Name: Thermal Shift Assay. Domain start/stop: M626-G740
Source: ChEMBL
Target: Peregrin
External Id: CHEMBL4650107

Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5062802

Name: Thermal Shift Assay. Domain: start/stop: M26-R383
Source: ChEMBL
Target: Glycogen synthase kinase-3 beta
External Id: CHEMBL5066381

Name: Thermal Shift Assay. Domain: start/stop: M626-G740
Source: ChEMBL
Target: Peregrin
External Id: CHEMBL5062665

Name: Thermal Shift Assay. Domain: start/stop: M26-R383
Source: ChEMBL
Target: Glycogen synthase kinase-3 beta
External Id: CHEMBL5065589

Name: Thermal Shift Assay. Domain: start/stop: S229-K512
Source: ChEMBL
Target: Tyrosine-protein kinase ABL1
External Id: CHEMBL5060015

Name: GPCR beta-arrestin recruitment assay with target: FPR2 Assay Type: PRESTO-Tango Conce...
Source: ChEMBL
Target: N-formyl peptide receptor 2
External Id: CHEMBL5209826

Name: GPCR beta-arrestin recruitment assay with target: GLP1R Assay Type: PRESTO-Tango Conc...
Source: ChEMBL
Target: Glucagon-like peptide 1 receptor
External Id: CHEMBL5209829

Name: GPCR beta-arrestin recruitment assay with target: FFAR4 Assay Type: PRESTO-Tango Conc...
Source: ChEMBL
Target: Free fatty acid receptor 4
External Id: CHEMBL5209823

Name: Thermal Shift Assay. Domain: start/stop: M1-S360
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL5067310

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7|A-hydroxycholesterol

7Alpha-Hydroxy Cholesterol

Cholest-5-en-3beta,7alpha-diol

Cholest-5-ene-3beta,7alpha-diol

(3S,7S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

7alpha-hydroxycholesterol

7alpha-Cholesterol

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Use of cholest-5-en-3β,7α-diol

Names

cholest-5-en-3β,7α-diol Biological Activity

Chemical & Physical Properties

Precursor & DownStream

cholest-5-en-3β,7α-diolBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.