3-Amino-4-methylpentanoic acid

Modify Date: 2024-01-09 16:12:28

3-Amino-4-methylpentanoic acid Structure
3-Amino-4-methylpentanoic acid structure
Common Name 3-Amino-4-methylpentanoic acid
CAS Number 5699-54-7 Molecular Weight 131.173
Density 1.0±0.1 g/cm3 Boiling Point 232.0±23.0 °C at 760 mmHg
Molecular Formula C6H13NO2 Melting Point 206-209ºC
MSDS Chinese USA Flash Point 94.1±22.6 °C

 Use of 3-Amino-4-methylpentanoic acid


3-Amino-4-methylpentanoic acid is a beta amino acid and positional isomer of L-leucine which is naturally produced in humans via the metabolism of L-leucine by the enzyme leucine 2,3-aminomutase.

 Names

Name (3R)-β-leucine
Synonym More Synonyms

 3-Amino-4-methylpentanoic acid Biological Activity

Description 3-Amino-4-methylpentanoic acid is a beta amino acid and positional isomer of L-leucine which is naturally produced in humans via the metabolism of L-leucine by the enzyme leucine 2,3-aminomutase.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 232.0±23.0 °C at 760 mmHg
Melting Point 206-209ºC
Molecular Formula C6H13NO2
Molecular Weight 131.173
Flash Point 94.1±22.6 °C
Exact Mass 131.094635
PSA 63.32000
LogP 0.37
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.463

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2922499990

 Synthetic Route

~59%

3-Amino-4-methylpentanoic acid Structure

3-Amino-4-methy...

CAS#:5699-54-7

Literature: Synthetic Communications, , vol. 28, # 2 p. 219 - 224

~41%

3-Amino-4-methylpentanoic acid Structure

3-Amino-4-methy...

CAS#:5699-54-7

Literature: Russian Journal of General Chemistry, , vol. 75, # 7 p. 1113 - 1124

~%

3-Amino-4-methylpentanoic acid Structure

3-Amino-4-methy...

CAS#:5699-54-7

Literature: Chemische Berichte, , vol. 91, p. 2383,2385

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles12

More Articles
Physiology and pathophysiology of organic acids in cerebrospinal fluid.

J. Inherit. Metab. Dis. 16(4) , 648-69, (1993)

Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...

Failure to detect beta-leucine in human blood or leucine 2,3-aminomutase in rat liver using capillary gas chromatography-mass spectrometry.

J. Biol. Chem. 263(12) , 5581-8, (1988)

It has been reported (Poston, J. (1976) J. Biol. Chem. 251, 1859-1863; (1982) 255, 10067-10072; (1984) 259, 2059-2061) that mammalian tissues contain an adenosylcobalamin-dependent enzyme, leucine 2,3...

Elevation of serum cystathionine levels in patients with cobalamin and folate deficiency.

Blood 81(12) , 3404-13, (1993)

Homocysteine can be methylated to form methionine by the cobalamin- (Cbl) and folate-dependent enzyme, methionine synthase; serum levels of total homocysteine are elevated in greater than 95% of patie...

 Synonyms

3-Amino-4-methylpentanoic acid
(3R)-beta-leucine
Pentanoic acid,3-amino-4-methyl
Pentanoic acid, 3-amino-4-methyl-
3-amino-4-methyl-valeric acid
3-Amino-4-methyl-pentanoic acid
MFCD00167975