tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Modify Date: 2024-01-01 21:34:59

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate structure
Common Name tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
CAS Number 571188-59-5 Molecular Weight 278.350
Density 1.2±0.1 g/cm3 Boiling Point 454.1±45.0 °C at 760 mmHg
Molecular Formula C14H22N4O2 Melting Point 130-132℃
MSDS N/A Flash Point 228.4±28.7 °C

 Names

Name tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 454.1±45.0 °C at 760 mmHg
Melting Point 130-132℃
Molecular Formula C14H22N4O2
Molecular Weight 278.350
Flash Point 228.4±28.7 °C
Exact Mass 278.174286
PSA 71.69000
LogP 1.23
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.569
Storage condition 2~8℃

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~99%

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: Imaeda, Yasuhiro; Kawamoto, Tetsuji; Tobisu, Mamoru; Konishi, Noriko; Hiroe, Katsuhiko; Kawamura, Masaki; Tanaka, Toshimasa; Kubo, Keiji Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 6 p. 3125 - 3140

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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: Journal of Medicinal Chemistry, , vol. 48, # 7 p. 2388 - 2406

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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: Journal of Medicinal Chemistry, , vol. 48, # 7 p. 2388 - 2406

~%

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: WO2011/140488 A1, ; WO 2011/140488 A1

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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: US2012/115878 A1, ;

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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: WO2012/97682 A1, ;

~%

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure

tert-Butyl 4-(6...

CAS#:571188-59-5

Literature: WO2012/97682 A1, ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

tert-Butyl-4-(6-aminopyridin-3-yl)piperazin-1-carboxylat
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
TERT BUTYL-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE-1-CARBOXYLATE
4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Ribociclib Intermediate 4
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