(9R)-6'-methoxycinchonan-9-ol

Modify Date: 2025-08-26 12:00:22

(9R)-6'-methoxycinchonan-9-ol Structure
(9R)-6'-methoxycinchonan-9-ol structure
Common Name (9R)-6'-methoxycinchonan-9-ol
CAS Number 572-59-8 Molecular Weight 324.41700
Density 1.218g/cm3 Boiling Point 495.88ºC at 760 mmHg
Molecular Formula C20H24N2O2 Melting Point 111-113°
MSDS Chinese USA Flash Point 253.699ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

 Use of (9R)-6'-methoxycinchonan-9-ol


Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM[1].

 Names

Name (R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Synonym More Synonyms

 (9R)-6'-methoxycinchonan-9-ol Biological Activity

Description Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM[1].
Related Catalog
Target

ggTas2r1[1]

References

[1]. Pizio AD, et, al. Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep. 2017 Aug 15;7(1):8223.

 Chemical & Physical Properties

Density 1.218g/cm3
Boiling Point 495.88ºC at 760 mmHg
Melting Point 111-113°
Molecular Formula C20H24N2O2
Molecular Weight 324.41700
Flash Point 253.699ºC
Exact Mass 324.18400
PSA 45.59000
LogP 3.11110
Index of Refraction 1.638
InChIKey LOUPRKONTZGTKE-AFHBHXEDSA-N
SMILES C=CC1CN2CCC1CC2C(O)c1ccnc2ccc(OC)cc12

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H302-H317-H334
Precautionary Statements P261-P280-P342 + P311
Hazard Codes Xn
Risk Phrases 22-42/43
Safety Phrases 22-36/37-45
RIDADR NONH for all modes of transport

 (9R)-6'-methoxycinchonan-9-olBioassay

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Name: uHTS identification of small molecule modulators of Rev-erb Alpha.
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: SBCCG-A1016-RevErbaLBD-Primary-Assay
Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
Name: Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H...
Source: Southern Research Institute
Target: CFTR
External Id: CF Folding
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
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1

 Synonyms

GNF-Pf-180
9-epi-Quinidine
Epiquinidine
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