Aureothricin

Modify Date: 2026-07-01 22:11:37

Aureothricin Structure
Aureothricin structure
Common Name Aureothricin
CAS Number 574-95-8 Molecular Weight 242.31800
Density 1.48g/cm3 Boiling Point 479.1ºC at 760 mmHg
Molecular Formula C9H10N2O2S2 Melting Point N/A
MSDS N/A Flash Point 243.6ºC

 Use of Aureothricin


Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].

 Names

Name N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)propanamide
Synonym More Synonyms

 Aureothricin Biological Activity

Description Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].
Related Catalog
Target

Bacteral[1]

References

[1]. Li B, et al. Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics. Nat Prod Rep. 2014 Jul;31(7):905-23.

 Chemical & Physical Properties

Density 1.48g/cm3
Boiling Point 479.1ºC at 760 mmHg
Molecular Formula C9H10N2O2S2
Molecular Weight 242.31800
Flash Point 243.6ºC
Exact Mass 242.01800
PSA 111.07000
LogP 2.61110
Index of Refraction 1.694
InChIKey UGZYFXMSMFMTSM-UHFFFAOYSA-N
SMILES CCC(=O)Nc1c2sscc-2n(C)c1=O

 AureothricinBioassay

View more

Name: Antimicrobial activity against Listeria monocytogenes CIP 82110 after 24 to 48 hrs by...
Source: ChEMBL
Target: Listeria monocytogenes
External Id: CHEMBL1166878
Name: Antimicrobial activity against Saccharomyces cerevisiae ATCC 4226 after 48 to 72 hrs ...
Source: ChEMBL
Target: Saccharomyces cerevisiae
External Id: CHEMBL1168898
Name: Antimicrobial activity against Staphylococcus aureus CIP 7625 after 24 to 48 hrs by a...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL1166877
Name: Antimicrobial activity against Candida albicans IPA 200 after 48 to 72 hrs by agar di...
Source: ChEMBL
Target: Candida albicans
External Id: CHEMBL1168897
Name: Antimicrobial activity against Micrococcus luteus ATCC 9314 after 24 to 48 hrs by aga...
Source: ChEMBL
Target: Micrococcus luteus
External Id: CHEMBL1166876
Name: Antimicrobial activity against Fusarium graminearum after 48 to 72 hrs by agar diluti...
Source: ChEMBL
Target: Fusarium graminearum
External Id: CHEMBL1168896
Name: Antimicrobial activity against Bacillus coagulans CIP 6625 after 24 to 48 hrs by agar...
Source: ChEMBL
Target: Heyndrickxia coagulans
External Id: CHEMBL1166875
Name: Antimicrobial activity against Fusarium culmorum after 48 to 72 hrs by agar dilution ...
Source: ChEMBL
Target: Fusarium culmorum
External Id: CHEMBL1168895
Name: Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 to 48 hrs by agar...
Source: ChEMBL
Target: Bacillus subtilis
External Id: CHEMBL1166874
Name: Antimicrobial activity against Fusarium equiseti after 48 to 72 hrs by agar dilution ...
Source: ChEMBL
Target: Fusarium equiseti
External Id: CHEMBL1168894
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 Synonyms

propionopyrrothine
Aureothricin
Anzeothricin
4-methyl-6-propionylamino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-one
N-(4-methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-propionamide
N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-propionamid
Farcinicin
Propiopyvothine
Aurethricin
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