1-tert-butyl-4,4-diphenylpiperidine

Modify Date: 2024-01-01 20:45:52

1-tert-butyl-4,4-diphenylpiperidine Structure
1-tert-butyl-4,4-diphenylpiperidine structure
 Common Name 1-tert-butyl-4,4-diphenylpiperidine
CAS Number 57982-78-2 Molecular Weight 293.446
Density 1.0±0.1 g/cm3 Boiling Point 387.6±42.0 °C at 760 mmHg
Molecular Formula C21H27N Melting Point 108.5°C
MSDS N/A Flash Point 168.7±24.8 °C

 Use of 1-tert-butyl-4,4-diphenylpiperidine


Budipine is an antiparkinsonian agent.

 Names

Name 1-tert-Butyl-4,4-diphenyl-piperidine
Synonym More Synonyms

 1-tert-butyl-4,4-diphenylpiperidine Biological Activity

Description Budipine is an antiparkinsonian agent.
Related Catalog
References

[1]. Reichmann H, et al. Budipine in Parkinson's tremor. J Neurol Sci. 2006 Oct 25;248(1-2):53-5.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 387.6±42.0 °C at 760 mmHg
Melting Point 108.5°C
Molecular Formula C21H27N
Molecular Weight 293.446
Flash Point 168.7±24.8 °C
Exact Mass 293.214355
PSA 3.24000
LogP 4.64
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.558

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM7291100
CHEMICAL NAME :
Piperidine, 1-(1,1-dimethylethyl)-4,4-diphenyl-
CAS REGISTRY NUMBER :
57982-78-2
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C21-H27-N
MOLECULAR WEIGHT :
293.49
WISWESSER LINE NOTATION :
T6NTJ AX1&1&1 DR& DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
165 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
33 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982

 Safety Information

HS Code 2933399090

 Synthetic Route

1-tert-Butylpiperidin-4-one structure

1-tert-Butylpip...

CAS#:1465-76-5
benzene structure

benzene

CAS#:71-43-2

~%

1-tert-butyl-4,4-diphenylpiperidine Structure

1-tert-butyl-4,...

CAS#:57982-78-2
Literature: Arzneimittel-Forschung/Drug Research, , vol. 34, # 3 p. 233 - 240

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Piperidine, 1-(1,1-dimethylethyl)-4,4-diphenyl-
1-(1,1-Dimethylethyl)-4,4-diphenyl-piperidine
1-tert-butyl-4,4-diphenylpiperidine
1-(2-Methyl-2-propanyl)-4,4-diphenylpiperidine
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Budipine
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

Get all suppliers and price by the below link:

1-tert-butyl-4,4-diphenylpiperidine suppliers

Price: ￥1928.4/250mg

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86840-39-3
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