布地平

• 常用名: 布地平
• 英文名: 1-tert-butyl-4,4-diphenylpiperidine
• CAS号: 57982-78-2
• 分子量: 293.446
• 密度: 1.0±0.1 g/cm3
• 沸点: 387.6±42.0 °C at 760 mmHg
• 分子式: C₂₁H₂₇N
• 熔点: 108.5°C
• 闪点: 168.7±24.8 °C

布地平用途

Budipine是一种抗帕金森病剂。

布地平名称

• 中文名: 布地平
• 英文名: 1-tert-Butyl-4,4-diphenyl-piperidine
• 中文别名: 布地品

布地平生物活性

• 描述: Budipine是一种抗帕金森病剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Reichmann H, et al. Budipine in Parkinson's tremor. J Neurol Sci. 2006 Oct 25;248(1-2):53-5.

布地平物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 387.6±42.0 °C at 760 mmHg
• 熔点: 108.5°C
• 分子式: C₂₁H₂₇N
• 分子量: 293.446
• 闪点: 168.7±24.8 °C
• 精确质量: 293.214355
• PSA: 3.24000
• LogP: 4.64
• InChIKey: QIHLUZAFSSMXHQ-UHFFFAOYSA-N
• SMILES: CC(C)(C)N1CCC(c2ccccc2)(c2ccccc2)CC1
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.558
• 储存条件: 库房通风低温干燥,与食品原料类分开存放

布地平毒性和生态

布地平安全信息

• 海关编码: 2933399090

布地平海关

• 海关编码: 2933399090
• 中文概述: 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

布地平靶点实验

查看更多实验

实验名称：Binding affinity towards human ADRA2A in an in vitro assay with cellular components m... 来源：ChEMBL 靶标：Alpha-2A adrenergic receptor External Id：CHEMBL5291736

实验名称：Binding affinity towards human GABRA1 in an in vitro assay with cellular components m... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit gamma-2 External Id：CHEMBL5291799

实验名称：Binding affinity towards human PGR in an in vitro assay with cellular components meas... 来源：ChEMBL 靶标：Progesterone receptor External Id：CHEMBL5291863

实验名称：Antagonist activity at human ADRA1A in an in vitro cell-based assay measured by fluor... 来源：ChEMBL 靶标：Alpha-1A adrenergic receptor External Id：CHEMBL5291731

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291792

实验名称：Binding affinity towards human ADORA3 (agonistic activity) in an in vitro assay with ... 来源：ChEMBL 靶标：Adenosine receptor A3 External Id：CHEMBL5291728

实验名称：Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay m... 来源：ChEMBL 靶标：cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A External Id：CHEMBL5291856

实验名称：Binding affinity towards human OPRM1 in an in vitro assay with cellular components me... 来源：ChEMBL 靶标：Mu-type opioid receptor External Id：CHEMBL5291855

实验名称：Agonist activity at human ADRA1A in an in vitro cell-based assay (CRO assay) measured... 来源：ChEMBL 靶标：Alpha-1A adrenergic receptor External Id：CHEMBL5291730

实验名称：Compound was evaluated for inhibition of human F2 in an in vitro cell free assay meas... 来源：ChEMBL 靶标：Prothrombin External Id：CHEMBL5291794

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布地平英文别名

• 1-(1,1-Dimethylethyl)-4,4-diphenyl-piperidine
• 1-tert-butyl-4,4-diphenylpiperidine
• 1-(2-Methyl-2-propanyl)-4,4-diphenylpiperidine