2-Nitronaphthalene

Modify Date: 2024-01-03 21:04:40

2-Nitronaphthalene structure	Common Name	2-Nitronaphthalene
	CAS Number	581-89-5	Molecular Weight	173.168
	Density	1.3±0.1 g/cm3	Boiling Point	319.6±11.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₇NO₂	Melting Point	65-73 °C
	MSDS	Chinese USA	Flash Point	158.7±12.1 °C
	Symbol	GHS02, GHS08, GHS09	Signal Word	Danger

Name	2-nitronaphthalene
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	319.6±11.0 °C at 760 mmHg
Melting Point	65-73 °C
Molecular Formula	C₁₀H₇NO₂
Molecular Weight	173.168
Flash Point	158.7±12.1 °C
Exact Mass	173.047684
PSA	45.82000
LogP	3.18
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.671

2-Nitronaphthalene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ9760000

CHEMICAL NAME :: Naphthalene, 2-nitro-

CAS REGISTRY NUMBER :: 581-89-5

BEILSTEIN REFERENCE NO. :: 2046354

LAST UPDATED :: 199801

DATA ITEMS CITED :: 26

MOLECULAR FORMULA :: C10-H7-N-O2

MOLECULAR WEIGHT :: 173.18

WISWESSER LINE NOTATION :: L66J CNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4400 mg/kg

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2650 mg/kg

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - methemoglobinemia-carboxyhemoglobin

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2400 mg/kg/34/W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 340 gm/kg/5Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Embryo

REFERENCE :: IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 19,642,1977 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,303,1989 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,303,1989 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,303,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWITZERLAND:TWA 0.035 ppm (0.25 mg/m3);Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 2-NITRONAPHTHALENE-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

Symbol	GHS02, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H228-H350-H411
Precautionary Statements	P201-P210-P273-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases	R45;R51/53
Safety Phrases	53-45-61-60
RIDADR	2538
WGK Germany	3
RTECS	QJ9760000
Packaging Group	III
Hazard Class	4.1
HS Code	2904209090

HS Code	2904209090
Summary	2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Comparative cytotoxicity of naphthalene and its monomethyl- and mononitro-derivatives in the mouse lung.

J. Appl. Toxicol. 6(1) , 13-20, (1986)

Male Swiss-Webster mice were exposed to naphthalene, 1-methyl-, 2-methyl-, 1-nitro- and 2-nitronaphthalene by intraperitoneal injection of peanut oil solutions over a dose range of 0.5-3.0 mmol kg-1 b...

Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes.

Mutat. Res. 608(1) , 88-96, (2006)

2,4-Diaminotoluene (2,4-DAT) is a liver carcinogen in rats and mice whereas 2,6-DAT is not. Both are genotoxic in vitro. Tests for mutations in transgenic mice, unscheduled DNA synthesis (UDS), DNA da...

1-nitronaphthalene.

IARC Monogr. Eval. Carcinog. Risks Hum. 46 , 303-12, (1989)

EINECS 209-474-5

MFCD00004055

2-Nitronaphthalene

Naphthalene, 2-nitro-

β-Nitronaphthalene

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-nitronaphthalene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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