4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide

Modify Date: 2025-08-22 17:50:37

4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide Structure
4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide structure
 Common Name 4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide
CAS Number 59197-86-3 Molecular Weight 339.29200
Density N/A Boiling Point N/A
Molecular Formula C14H8F3N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C14H8F3N3O2S
Molecular Weight 339.29200
Exact Mass 339.02900
PSA 106.58000
LogP 3.63970
InChIKey SUZLPICITRHWOF-UHFFFAOYSA-N
SMILES O=C(Nc1nccs1)c1c[nH]c2c(C(F)(F)F)cccc2c1=O

 Bioassay

View more

Name: Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administratio...
Source: ChEMBL
Target: Polyunsaturated fatty acid 5-lipoxygenase
External Id: CHEMBL618064
Name: Ulcerogenic effect against intestinal ulcer in rats after oral administration of 500 ...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL777718
Name: Analgesic activity against acetic acid induced writhing test in mouse after peroral a...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL731702
Name: Antiinflammatory activity against carrageenan-induced foot edema in rat after peroral...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL783175
Name: Inhibition of bovine Prostaglandin G/H synthase after oral administration
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL767498
Name: Antiinflammatory activity against carrageenan-induced foot edema in rat after peroral...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL783794
Name: Analgesic activity against acetic acid induced writhing test in mouse after peroral a...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL731695
Name: Antiarthritis activity against adjuvant-induced arthritis in rats at 50 mg/kg; IA=Ina...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL784391
Name: Ulcerogenic effect against gastric ulcer in rat after oral administration
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL779163
Total 9, Current Page 1 of 1
1

 Synonyms

3-Quinolinecarboxamide,4-hydroxy-N-2-thiazolyl-8-(trifluoromethyl)
N-[2-thiazolyl]-4-hydroxy-8-trifluoromethyl-3-quinoline-carboxamide
4-hydroxy-N-(2-thiazolyl)-8-trifluoromethyl 3-quinoline carboxamide
F3350-0898
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Chemsrc provides CAS#:59197-86-3 MSDS, density, melting point, boiling point, structure, etc. Its name is 4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide>> amp version: 4-oxo-N-(1,3-thiazol-2-yl)-8-(trifluoromethyl)-1H-quinoline-3-carboxamide

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