Mating Factor α acetate salt

Modify Date: 2024-01-03 11:18:34

Mating Factor α acetate salt structure	Common Name	Mating Factor α acetate salt
	CAS Number	59401-28-4	Molecular Weight	1683.97000
	Density	1.338 g/cm3	Boiling Point	1995.8ºC at 760 mmHg
	Molecular Formula	C₈₂H₁₁₄N₂₀O₁₇S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Mating Factor α acetate salt

α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.

Name	α(1)-mating factor
Synonym	More Synonyms

Description	α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Peptides
Target	Ste2p[1]
In Vitro	α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells[1]. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35S-α-factor to haploid a cells, with Kd of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability[2].
References	[1]. Naider F, et al. The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides. 2004 Sep;25(9):1441-63. [2]. Jenness DD, et al. Binding of alpha-factor pheromone to yeast a cells: chemical and genetic evidence for an alpha-factor receptor. Cell. 1983 Dec;35(2 Pt 1):521-9.

Density	1.338 g/cm3
Boiling Point	1995.8ºC at 760 mmHg
Molecular Formula	C₈₂H₁₁₄N₂₀O₁₇S
Molecular Weight	1683.97000
Exact Mass	1682.84000
PSA	612.93000
LogP	6.31310
Index of Refraction	1.625
Storage condition	−20°C
Water Solubility	H2O: 1 mg/mL, clear, colorless \| Soluble in water at 1mg/ml

Mating Factor α acetate salt MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

Synthesis of the mating factor of Saccharomyces cerevisiae and its truncated peptides : the structure-activity relationship.

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Mol. Cancer Ther. 28 , 988-96, (2008)

We report that the histone acetyltransferase Gcn5p is involved in cell cycle progression, whereas its absence induces several mitotic defects, including inefficient nuclear division, chromosome loss, ...

alpha1-Mating Factor acetate salt

alpha1-MATING FACTOR

MFCD00133883

Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

A1-Mating Factor acetate salt

WHWLQLKPGQPMY

α-Factor Mating Pheromone, yeast