Cetylpyridinium chloride monohydrate

Modify Date: 2024-01-04 10:04:00

Cetylpyridinium chloride monohydrate Structure
Cetylpyridinium chloride monohydrate structure
Common Name Cetylpyridinium chloride monohydrate
CAS Number 6004-24-6 Molecular Weight 358.001
Density N/A Boiling Point N/A
Molecular Formula C21H40ClNO Melting Point 81-84 °C
MSDS Chinese USA Flash Point N/A
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Use of Cetylpyridinium chloride monohydrate


Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound, used in some types of mouthwashes, toothpastes, throat and nasal sprays, is an antiseptic that kills bacteria and other microorganisms, effective in preventing dental plaque and reducing gingivitis.

 Names

Name cetylpyridinium chloride monohydrate
Synonym More Synonyms

 Cetylpyridinium chloride monohydrate Biological Activity

Description Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound, used in some types of mouthwashes, toothpastes, throat and nasal sprays, is an antiseptic that kills bacteria and other microorganisms, effective in preventing dental plaque and reducing gingivitis.
Related Catalog

 Chemical & Physical Properties

Melting Point 81-84 °C
Molecular Formula C21H40ClNO
Molecular Weight 358.001
Exact Mass 357.279846
PSA 13.11000
LogP 3.39510
Stability Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU5075000
CHEMICAL NAME :
Pyridinium, 1-hexadecyl-, chloride, monohydrate
CAS REGISTRY NUMBER :
6004-24-6
LAST UPDATED :
199603
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C21-H38-N.Cl.H2-O
MOLECULAR WEIGHT :
358.07
WISWESSER LINE NOTATION :
T6KJ A16 &G &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H315-H319-H330-H335-H410
Precautionary Statements P260-P304 + P340 + P310-P305 + P351 + P338-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T+:Verytoxic;
Risk Phrases R25;R26;R38
Safety Phrases S28-S36/37-S45-S7/9-S61-S26
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS UU5075000
Packaging Group I
Hazard Class 6.1
HS Code 2933399090

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Cetylpyridinum chloride
Cetylpyridinium chloride monohydrate
CETYLPYRIDINII CHLORIDUM
MFCD00149977
CPC MONOHYDRATE
EINECS 204-593-9
Pyridinium, 1-hexadecyl-, chloride, hydrate (1:1:1)
cetylpyridinium chloride
Chlorohexadecyl pyridine
Ceetylpyridiniumchloride
1-Hexadecylpyridin-1-ium chloride hydrate
Cetylpyridinium chloride hydrate
hexadecylpyridium chloride
cetyl pyridium chloride
1-Hexadecylpyridinium chloride hydrate (1:1:1)
Halset
N-CETYLPYRIDINIUM CHLORIDE MONOHYDRATE
Hexadecylpyridinium Chloride Monohydrate
Dobendan
Sprol
1-cetylpyridin-1-ium chloride hydrate
CPC
1-hexadecylpyridinium chloride monohydrate
N-hexadecylpyridinium chloride monohydrate
CPC hydrate
CETYL PYRIDIMUM CHLORIDE
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