Taspine
Taspine structure
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Common Name | Taspine | ||
|---|---|---|---|---|
| CAS Number | 602-07-3 | Molecular Weight | 369.36800 | |
| Density | 1.35g/cm3 | Boiling Point | 569.6ºC at 760 mmHg | |
| Molecular Formula | C20H19NO6 | Melting Point | >300ºC (dec.) | |
| MSDS | N/A | Flash Point | 298.3ºC | |
Use of TaspineTaspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Taspine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.35g/cm3 |
|---|---|
| Boiling Point | 569.6ºC at 760 mmHg |
| Melting Point | >300ºC (dec.) |
| Molecular Formula | C20H19NO6 |
| Molecular Weight | 369.36800 |
| Flash Point | 298.3ºC |
| Exact Mass | 369.12100 |
| PSA | 82.12000 |
| LogP | 2.61170 |
| Index of Refraction | 1.62 |
| InChIKey | MTAWKURMWOXCEO-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(=O)oc3c(OC)cc(CCN(C)C)c4c(=O)oc1c2c34 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
![3,8-dimethoxy-1-(2-oxoethyl)[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione structure](https://image.chemsrc.com/caspic/279/216374-60-6.png)
![1-iodo-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione structure](https://image.chemsrc.com/caspic/172/216374-58-2.png)
![5,5'-dimethoxy-6,6'-bis(methoxymethoxy)-N2,N2'-dipropyl-[1,1'-biphenyl]-2,2'-dicarboxamide structure](https://image.chemsrc.com/caspic/210/216374-57-1.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 1 | |
CAS#:35115-50-5This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Cytotoxicity against HUVEC cell at 25 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022664
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Name: Teratogenic activity in rat embryo assessed as incidence of major malformation at 5 u...
Source: ChEMBL
Target: N/A
External Id: CHEMBL966343
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Name: Effect on growth and morphogenesis of organogenesis-staged rat embryo at 50 ug/mL aft...
Source: ChEMBL
Target: N/A
External Id: CHEMBL966339
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Name: Embryotoxicity in rat embryo at 250 ug/mL
Source: ChEMBL
Target: N/A
External Id: CHEMBL966350
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Name: Cytotoxicity against HUVEC cell at 2.5 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022666
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Name: Cytotoxicity against HUVEC cell at 5 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022665
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Name: Induction of HUVEC cell proliferation at 0.25 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022668
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-(2-Dimethylamino-aethyl)-3,8-dimethoxy-chromeno[5,4,3-cde]chromen-5,10-dion |
| 1-[2-(dimethylamino)ethyl]-3,8-dimethoxy-1-(2-oxoethyl)[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione |
| 3,8-Dimethoxy-1-[2-(dimethylamino)ethyl][1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione |
| 1-[2-(dimethylamino)ethyl]-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of Taspine? |
| A: Molecular formula of Taspine is C20H19NO6. |
| Q: What is the InChIKey of Taspine? |
| A: InChIKey of Taspine is MTAWKURMWOXCEO-UHFFFAOYSA-N. |
| Q: What is the melting point of Taspine? |
| A: Melting point of Taspine is >300ºC (dec.). |
| Q: What are the downstream products of Taspine? |
| A: Related downstream products(CAS) of Taspine: 35115-50-5. |
| Q: What is the boiling point of Taspine? |
| A: Boiling point of Taspine is 569.6ºC at 760 mmHg. |
| Q: What is the CAS number of Taspine? |
| A: CAS number of Taspine is 602-07-3. |
| Q: What is the English name of Taspine? |
| A: The English name of Taspine is Taspine. |
| Q: What English synonyms does Taspine have? |
| A: English synonyms of Taspine: 1-(2-Dimethylamino-aethyl)-3,8-dimethoxy-chromeno[5,4,3-cde]chromen-5,10-dion, 1-[2-(dimethylamino)ethyl]-3,8-dimethoxy-1-(2-oxoethyl)[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 3,8-Dimethoxy-1-[2-(dimethylamino)ethyl][1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 1-[2-(dimethylamino)ethyl]-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione. |
| Q: What are the upstream materials of Taspine? |
| A: Related upstream materials(CAS) of Taspine: 124-40-3;216374-60-6;216374-54-8;216374-55-9;216374-56-0;216374-58-2;216374-59-3;50-00-0. |
| Q: What are the uses of Taspine? |
| A: Main uses of Taspine: Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1]. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |