Taspine
Modify Date: 2025-08-26 20:25:21
Taspine structure
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Common Name | Taspine | ||
|---|---|---|---|---|
| CAS Number | 602-07-3 | Molecular Weight | 369.36800 | |
| Density | 1.35g/cm3 | Boiling Point | 569.6ºC at 760 mmHg | |
| Molecular Formula | C20H19NO6 | Melting Point | >300ºC (dec.) | |
| MSDS | N/A | Flash Point | 298.3ºC | |
Use of TaspineTaspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1]. |
| Name | Taspine |
|---|---|
| Synonym | More Synonyms |
| Description | Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.35g/cm3 |
|---|---|
| Boiling Point | 569.6ºC at 760 mmHg |
| Melting Point | >300ºC (dec.) |
| Molecular Formula | C20H19NO6 |
| Molecular Weight | 369.36800 |
| Flash Point | 298.3ºC |
| Exact Mass | 369.12100 |
| PSA | 82.12000 |
| LogP | 2.61170 |
| Index of Refraction | 1.62 |
| InChIKey | MTAWKURMWOXCEO-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(=O)oc3c(OC)cc(CCN(C)C)c4c(=O)oc1c2c34 |
![3,8-dimethoxy-1-(2-oxoethyl)[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione structure](https://image.chemsrc.com/caspic/279/216374-60-6.png)
![1-iodo-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione structure](https://image.chemsrc.com/caspic/172/216374-58-2.png)
![5,5'-dimethoxy-6,6'-bis(methoxymethoxy)-N2,N2'-dipropyl-[1,1'-biphenyl]-2,2'-dicarboxamide structure](https://image.chemsrc.com/caspic/210/216374-57-1.png)
| Precursor 8 | |
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| DownStream 1 | |
CAS#:35115-50-5|
Name: Cytotoxicity against HUVEC cell at 25 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022664
|
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Name: Teratogenic activity in rat embryo assessed as incidence of major malformation at 5 u...
Source: ChEMBL
Target: N/A
External Id: CHEMBL966343
|
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Name: Effect on growth and morphogenesis of organogenesis-staged rat embryo at 50 ug/mL aft...
Source: ChEMBL
Target: N/A
External Id: CHEMBL966339
|
|
Name: Embryotoxicity in rat embryo at 250 ug/mL
Source: ChEMBL
Target: N/A
External Id: CHEMBL966350
|
|
Name: Cytotoxicity against HUVEC cell at 2.5 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022666
|
|
Name: Cytotoxicity against HUVEC cell at 5 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022665
|
|
Name: Induction of HUVEC cell proliferation at 0.25 ug/ml after 6 days
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1022668
|
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| 1-(2-Dimethylamino-aethyl)-3,8-dimethoxy-chromeno[5,4,3-cde]chromen-5,10-dion |
| 1-[2-(dimethylamino)ethyl]-3,8-dimethoxy-1-(2-oxoethyl)[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione |
| 3,8-Dimethoxy-1-[2-(dimethylamino)ethyl][1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione |
| 1-[2-(dimethylamino)ethyl]-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione |