Desacetyl Bisacodyl

Modify Date: 2025-08-21 17:50:18

Desacetyl Bisacodyl structure	Common Name	Desacetyl Bisacodyl
	CAS Number	603-41-8	Molecular Weight	277.32
	Density	1.244g/cm3	Boiling Point	462.1ºC at 760 mmHg
	Molecular Formula	C₁₈H₁₅NO₂	Melting Point	>200ºC (dec.)
	MSDS	N/A	Flash Point	233.3ºC

Use of Desacetyl Bisacodyl

Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].

Name	4-[(4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol
Synonym	More Synonyms

Description	Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Fujita T, et, al. Desacetyl bisacodyl-induced epithelial Cl(-) secretion in rat colon and rectum. Biomed Res. 2016;37(1):13-20.

Density	1.244g/cm3
Boiling Point	462.1ºC at 760 mmHg
Melting Point	>200ºC (dec.)
Molecular Formula	C₁₈H₁₅NO₂
Molecular Weight	277.32
Flash Point	233.3ºC
Exact Mass	277.11000
PSA	53.35000
LogP	3.67300
Index of Refraction	1.655

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM8730000

CHEMICAL NAME :: Phenol, 4,4'-(2-pyridylmethylene)di-

CAS REGISTRY NUMBER :: 603-41-8

BEILSTEIN REFERENCE NO. :: 0212040

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H15-N-O2

MOLECULAR WEIGHT :: 277.34

WISWESSER LINE NOTATION :: T6NJ BYR DQ&R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8550 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NAIZAM Nara Igaku Zasshi. Journal of the Nara Medical Association. (Nara Igakkai, c/o Narakenritsu Ika Daigaku, Shijo-cho, Kashihara, Nara-ken, Japan) V.1- 1950- Volume(issue)/page/year: 28,258,1977

RIDADR	NONH for all modes of transport

4,4'-pyridin-2-ylmethanediyl-bis-phenol

EINECS 210-039-7

Deacetylbisocodyl

DDPM

La-96

deacetylbisacodyl

Dihydroxydiphenyl-pyridyl methane

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Desacetyl Bisacodyl

Use of Desacetyl Bisacodyl

Names

Desacetyl Bisacodyl Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.