Desacetyl Bisacodyl

Modify Date: 2024-01-09 23:27:34

Desacetyl Bisacodyl structure	Common Name	Desacetyl Bisacodyl
	CAS Number	603-41-8	Molecular Weight	277.32
	Density	1.244g/cm3	Boiling Point	462.1ºC at 760 mmHg
	Molecular Formula	C₁₈H₁₅NO₂	Melting Point	>200ºC (dec.)
	MSDS	N/A	Flash Point	233.3ºC

Use of Desacetyl Bisacodyl

Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].

Name	4-[(4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol
Synonym	More Synonyms

Description	Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Fujita T, et, al. Desacetyl bisacodyl-induced epithelial Cl(-) secretion in rat colon and rectum. Biomed Res. 2016;37(1):13-20.

Density	1.244g/cm3
Boiling Point	462.1ºC at 760 mmHg
Melting Point	>200ºC (dec.)
Molecular Formula	C₁₈H₁₅NO₂
Molecular Weight	277.32
Flash Point	233.3ºC
Exact Mass	277.11000
PSA	53.35000
LogP	3.67300
Index of Refraction	1.655

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM8730000

CHEMICAL NAME :: Phenol, 4,4'-(2-pyridylmethylene)di-

CAS REGISTRY NUMBER :: 603-41-8

BEILSTEIN REFERENCE NO. :: 0212040

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H15-N-O2

MOLECULAR WEIGHT :: 277.34

WISWESSER LINE NOTATION :: T6NJ BYR DQ&R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8550 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NAIZAM Nara Igaku Zasshi. Journal of the Nara Medical Association. (Nara Igakkai, c/o Narakenritsu Ika Daigaku, Shijo-cho, Kashihara, Nara-ken, Japan) V.1- 1950- Volume(issue)/page/year: 28,258,1977

RIDADR	NONH for all modes of transport

4,4'-pyridin-2-ylmethanediyl-bis-phenol

EINECS 210-039-7

Deacetylbisocodyl

DDPM

La-96

deacetylbisacodyl

Dihydroxydiphenyl-pyridyl methane

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

Desacetyl Bisacodyl

Use of Desacetyl Bisacodyl

Names

Desacetyl Bisacodyl Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Synonyms