1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE

Modify Date: 2026-08-03 17:26:31

1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE structure	Common Name	1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE
	CAS Number	60569-19-9	Molecular Weight	367.48
	Density	1.08 g/cm3	Boiling Point	468.8ºC at 760 mmHg
	Molecular Formula	C₂₃H₂₉NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	134.6ºC

Use of 1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE

Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].

Name	(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate
Synonym	More Synonyms

Description	Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91. [2]. Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35.

Description

Related Catalog

Signaling Pathways >> Neuronal Signaling >> mAChR

Signaling Pathways >> GPCR/G Protein >> mAChR

Research Areas >> Neurological Disease

References

[1]. McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91.

[2]. Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35.

Density	1.08 g/cm3
Boiling Point	468.8ºC at 760 mmHg
Molecular Formula	C₂₃H₂₉NO₃
Molecular Weight	367.48
Flash Point	134.6ºC
Exact Mass	367.21500
PSA	38.77000
LogP	3.93210
Index of Refraction	1.57
InChIKey	QPCVHQBVMYCJOM-UHFFFAOYSA-N
SMILES	CCCOC(C(=O)OC1CCN(C)CC1)(c1ccccc1)c1ccccc1

HS Code	2933399090

Propiverine hyd...

CAS#:54556-98-8

1-METHYLPIPERID...

CAS#:60569-19-9

Learn More

Literature: WO2014/39627 A1, ; Page/Page column 126 ;

Precursor 1
CAS#:54556-98-8 Propiverine hyd...
DownStream 1
CAS#:3608-67-1 enpiperate

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Name: Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291801

Name: Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291798

Name: Human intestinal absorption in po dosed human
Source: ChEMBL
Target: Homo sapiens
External Id: CHEMBL1116254

Name: Antagonist activity human CHRM1 in an in vitro cell-based assay measured by fluoresce...
Source: ChEMBL
Target: Muscarinic acetylcholine receptor M1
External Id: CHEMBL5291920

Name: Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL5291791

Name: Binding affinity towards human HRH3 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: Histamine H3 receptor
External Id: CHEMBL5291921

Name: Binding affinity towards human EDNRA in an in vitro assay with cellular components me...
Source: ChEMBL
Target: Endothelin-1 receptor
External Id: CHEMBL5291785

Name: S16 Schwann cell viability assay (CellTiter-Glo assay)
Source: NCGC
Target: N/A
External Id: cmt-p4-fda-celltiter_regid

Name: Binding affinity towards human DRD2 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: D(2) dopamine receptor
External Id: CHEMBL5291781

Name: Biochemical firefly luciferase enzyme assay for NPC
Source: NCGC
Target: Luciferase [Photinus pyralis]
External Id: adst-fluc-km-fda-o1_regid

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Propiverine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Propiverine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Use of 1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.