Cyclic-di-GMP

Modify Date: 2024-01-07 16:44:04

Cyclic-di-GMP Structure
Cyclic-di-GMP structure
Common Name Cyclic-di-GMP
CAS Number 61093-23-0 Molecular Weight 690.41100
Density N/A Boiling Point N/A
Molecular Formula C20H24N10O14P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cyclic-di-GMP


Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.

 Names

Name c-di-GMP
Synonym More Synonyms

 Cyclic-di-GMP Biological Activity

Description Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.
Related Catalog
Target

STING[1]

References

[1]. Nakamura T, et al. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma. J Control Release. 2015 Oct 28;216:149-57.

[2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.

 Chemical & Physical Properties

Molecular Formula C20H24N10O14P2
Molecular Weight 690.41100
Exact Mass 690.09500
PSA 371.22000
Storage condition 2-8℃

 Synonyms

Cyclic diguanylate
cyclic di-GMP
3',5'-Cyclic diguanylic acid
Cyclic-di-GMP
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