BMS-561392

Modify Date: 2024-09-17 20:49:21

BMS-561392 Structure
BMS-561392 structure
Common Name BMS-561392
CAS Number 611227-74-8 Molecular Weight 476.57
Density N/A Boiling Point N/A
Molecular Formula C27H32N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-561392


BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. BMS-561392 is also an ADAM17 blocker. BMS-561392 can be used for research of inflammatory bowel disease[1][2].

 Names

Name BMS-561392

 BMS-561392 Biological Activity

Description BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. BMS-561392 is also an ADAM17 blocker. BMS-561392 can be used for research of inflammatory bowel disease[1][2].
Related Catalog
References

[1]. Kim ML, et al. Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo. J Neurosci. 2008 Nov 12;28(46):12052-61.  

[2]. Vidal PM, et al. ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice. Cell Death Dis. 2013 Dec 12;4(12):e954.  

 Chemical & Physical Properties

Molecular Formula C27H32N4O4
Molecular Weight 476.57
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