VU0152099 structure
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Common Name | VU0152099 | ||
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CAS Number | 612514-42-8 | Molecular Weight | 355.411 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 622.9±55.0 °C at 760 mmHg | |
Molecular Formula | C18H17N3O3S | Melting Point | N/A | |
MSDS | N/A | Flash Point | 330.5±31.5 °C |
Use of VU0152099VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM; shows no agonist activity but potentiates responses of M(4) to acetylcholine, and is devoid of activity at other mAChR subtypes or at a panel of other GPCRs; reverses amphetamine-induced hyperlocomotion in rats. |
Name | VU0152099 |
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Synonym | More Synonyms |
Description | VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM; shows no agonist activity but potentiates responses of M(4) to acetylcholine, and is devoid of activity at other mAChR subtypes or at a panel of other GPCRs; reverses amphetamine-induced hyperlocomotion in rats. |
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References | References 1. Brady AE, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):941-53. View Related Products by Target mAChR |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 622.9±55.0 °C at 760 mmHg |
Molecular Formula | C18H17N3O3S |
Molecular Weight | 355.411 |
Flash Point | 330.5±31.5 °C |
Exact Mass | 355.099060 |
LogP | 4.32 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.708 |
3-Amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide |
Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethyl- |
VU0152099 |