TRX-0237
Modify Date: 2025-08-25 17:56:35
TRX-0237 structure
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Common Name | TRX-0237 | ||
|---|---|---|---|---|
| CAS Number | 613-11-6 | Molecular Weight | 285.40700 | |
| Density | 1.201g/cm3 | Boiling Point | 491.7ºC at 760 mmHg | |
| Molecular Formula | C16H19N3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 251.2ºC | |
Use of TRX-0237TRX-0237 Methylate (Hydromethylthionine, Methylene blue) is a Tau aggregation inhibitor (TAI) with Ki of 0.12 uM for intracellular TAI activity. |
| Name | 3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine |
|---|---|
| Synonym | More Synonyms |
| Density | 1.201g/cm3 |
|---|---|
| Boiling Point | 491.7ºC at 760 mmHg |
| Molecular Formula | C16H19N3S |
| Molecular Weight | 285.40700 |
| Flash Point | 251.2ºC |
| Exact Mass | 285.13000 |
| PSA | 43.81000 |
| LogP | 4.16480 |
| Index of Refraction | 1.675 |
| InChIKey | QTWZICCBKBYHDM-UHFFFAOYSA-N |
| SMILES | CN(C)c1ccc2c(c1)Sc1cc(N(C)C)ccc1N2 |
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Name: Dissociation constant, pKa of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL1023579
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Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
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Name: Experimentally measured binding affinity data (Ki) for protein-ligand complexes deriv...
Source: Shanghai Institute of Organic Chemistry
Target: N/A
External Id: PDBbind-Ki for protein-ligand complexes
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Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
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Name: Inhibition of congo red-induced EGFP-tagged Tau P301L mutant (unknown origin) aggrega...
Source: ChEMBL
Target: Microtubule-associated protein tau
External Id: CHEMBL4236009
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Name: Protection against amyloid beta oligomer-induced cytotoxicity in human SH-SY5Y cells ...
Source: ChEMBL
Target: SH-SY5Y
External Id: CHEMBL4669397
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Total 6, Current Page 1 of 1
1
| leucoform |
| Reduced methylene blue |
| N,N,N',N'-Tetramethyl-10H-phenothiazine-3,7-diamine |
| Panatone |
| Leukomethylene blue |
| N3,N3,N7,N7-tetramethyl-10H-phenothiazine-3,7-diamine |
| methylene white |
| 2w9i |
| Leucomethylene blue |