Diethylformamide

Modify Date: 2024-01-02 13:08:51

Diethylformamide Structure
Diethylformamide structure
Common Name Diethylformamide
CAS Number 617-84-5 Molecular Weight 101.147
Density 0.9±0.1 g/cm3 Boiling Point 177.5±0.0 °C at 760 mmHg
Molecular Formula C5H11NO Melting Point 176-177°C
MSDS Chinese USA Flash Point 60.6±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Use of Diethylformamide


N,N-Diethylformamide is an Industrial solvent claimed to have HIV protease inhibitory action.

 Names

Name N,N-Diethylformamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 177.5±0.0 °C at 760 mmHg
Melting Point 176-177°C
Molecular Formula C5H11NO
Molecular Weight 101.147
Flash Point 60.6±0.0 °C
Exact Mass 101.084061
PSA 20.31000
LogP 0.05
Vapour Pressure 1.0±0.3 mmHg at 25°C
Index of Refraction 1.418

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ1925000
CHEMICAL NAME :
Formamide, N,N-diethyl-
CAS REGISTRY NUMBER :
617-84-5
BEILSTEIN REFERENCE NO. :
1209392
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H11-N-O
MOLECULAR WEIGHT :
101.17
WISWESSER LINE NOTATION :
VHN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1740 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 85,72,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1740 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,330,1986
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,409,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6943 No. of Facilities: 49 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 6718 (estimated)

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR UN 1993 3/PG 3
WGK Germany 1
RTECS LQ1925000
Packaging Group III
Hazard Class 3
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles8

More Articles
Fabrication of porous cubic architecture of ZnO using Zn-terephthalate MOFs with characteristic microstructures.

Inorg. Chem. 52(24) , 14028-33, (2013)

A method for synthesizing porous cubic-shaped ZnO particles a few tens of micrometers in size is described on the basis of a pyrolytic conversion of Zn-terephthalate metal-organic frameworks (MOFs). M...

A new and facile synthesis of quinazoline-2,4(1H,3H)-diones.

Org. Lett. 11(6) , 1193-6, (2009)

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl(2) (0.5...

Metal-catalyzed reduction of HCONR'2, R' = Me (DMF), Et (DEF), by silanes to produce R'2NMe and disiloxanes: a mechanism unraveled.

J. Am. Chem. Soc. 134(2) , 848-51, (2012)

We demonstrate that using Mo(CO)(6), Mo(CO)(5)NMe(3), and (η(5)-C(5)H(5))Mn(CO)(3) as catalysts for the silane, R(3)SiH, reduction of N,N-dimethylformamide (DMF), and N,N-diethylformamide (DEF), we ca...

 Synonyms

Diethylformamide
N,N-Diethylformamide
Formamide, N,N-diethyl-
EINECS 210-533-2
MFCD00003287
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